Associations among maternal childhood socioeconomic status, cord blood IgE levels, and repeated wheeze in urban children Michelle J. Sternthal, PhD,

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Presentation transcript:

Associations among maternal childhood socioeconomic status, cord blood IgE levels, and repeated wheeze in urban children Michelle J. Sternthal, PhD, Brent A. Coull, PhD, Yueh-Hsiu Mathilda Chiu, ScD, Sheldon Cohen, PhD, Rosalind J. Wright, MD, MPH Journal of Allergy and Clinical Immunology Volume 128, Issue 2, Pages 337-345.e1 (August 2011) DOI: 10.1016/j.jaci.2011.05.008 Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Significant pathways linking low maternal childhood SES to repeated wheeze in offspring. Ovals represent unmeasured latent variables, and boxes represent measured variables. Shaded areas represent prenatal social and physical environmental exposures considered in analyses. All models adjust for maternal atopy/asthma, nativity status, child’s sex, and race. Bolded lines represent significant pathways, and dotted lines represent nonsignificant pathways. Coefficients are listed only for significant pathways. Effect estimates for all tested direct and indirect pathways are provided in the Online Repository (see Table E1). A positive sign indicates that the probability of the categorical dependent variable is increased when the predictor increases. ∗∗∗P < .001, ∗∗P < .01, ∗P < .05, and +P < .10. Journal of Allergy and Clinical Immunology 2011 128, 337-345.e1DOI: (10.1016/j.jaci.2011.05.008) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Significant pathways linking low maternal childhood SES to increased cord blood IgE levels. Ovals represent unmeasured latent variables, and boxes represent measured variables. Shaded areas represent prenatal social and physical environmental exposures considered in analyses. All models adjust for maternal asthma/atopy, nativity status, child’s sex, and race. Bolded lines represent significant pathways, and dotted lines represent non-significant pathways. Coefficients are listed only for significant pathways. Effect estimates for all tested direct and indirect pathways are provided in the Online Repository (see Table E1). A positive sign indicates that the probability of the categorical dependent variable is increased when the predictor variable increases. ∗∗∗P < .001, ∗∗P < .01, ∗P < .05. Journal of Allergy and Clinical Immunology 2011 128, 337-345.e1DOI: (10.1016/j.jaci.2011.05.008) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions