Exposure to a farming environment has allergen-specific protective effects on TH2- dependent isotype switching in response to common inhalants Debra A.

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Presentation transcript:

Exposure to a farming environment has allergen-specific protective effects on TH2- dependent isotype switching in response to common inhalants Debra A. Stern, MS, Josef Riedler, MD, Dennis Nowak, MD, Charlotte Braun-Fahrlander, MD, Ines Swoboda, PhD, Nadja Balic, Kuan- Wei Chen, MSc, Susanne Vrtala, PhD, Hans Grönlund, PhD, Marianne van Hage, MD, PhD, Rudolf Valenta, MD, Susanne Spitzauer, MD, Erika Von Mutius, MD, Donata Vercelli, MD Journal of Allergy and Clinical Immunology Volume 119, Issue 2, Pages 351-358 (February 2007) DOI: 10.1016/j.jaci.2006.10.013 Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Effects of farm exposure on patterns of immunoglobulin production to rPhl p 1 (A), rFel d 1 (B), and rDer p 2 (C). F, Farm exposure; NF, no farm exposure. The P values are associated with the comparison of response rates between farm-exposed and non–farm-exposed children by means of χ2 analysis. Significant P values are reported in red. For comparisons with response rates of 0, no statistics were computed (NT). Journal of Allergy and Clinical Immunology 2007 119, 351-358DOI: (10.1016/j.jaci.2006.10.013) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions