Comparative decades of experience with glutaraldehyde-tanned human umbilical cord vein graft for lower limb revascularization: An analysis of 1275 cases

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Presentation transcript:

Comparative decades of experience with glutaraldehyde-tanned human umbilical cord vein graft for lower limb revascularization: An analysis of 1275 cases Herbert Dardik, MD, Kurt Wengerter, MD, Feng Qin, MD, Audwin Pangilinan, MD, Fred Silvestri, MD, Fred Wolodiger, MD, Mark Kahn, MD, Barry Sussman, MD, Ibrahim M. Ibrahim, MD Journal of Vascular Surgery Volume 35, Issue 1, Pages 64-71 (January 2002) DOI: 10.1067/mva.2002.121053 Copyright © 2002 Society for Vascular Surgery and The American Association for Vascular Surgery Terms and Conditions

Fig. 1 Numbers and types of umbilical vein grafts implanted from 1975 to 2000. Grafts implanted since 1990 were prepared by new manufacturer. Each bar since 1986 represents total umbilical vein bypass grafts for that year. Bottom numbers are popliteals, and above those are crurals. See Dardik et al15 for details for first decade. UV, Umbilical vein graft; Pop, popliteal. Journal of Vascular Surgery 2002 35, 64-71DOI: (10.1067/mva.2002.121053) Copyright © 2002 Society for Vascular Surgery and The American Association for Vascular Surgery Terms and Conditions

Fig. 2 Type, number, and percentage of distal anastomoses of umbilical vein grafts for 1990 to 2000. Shift of 10% occurred from popliteals to crurals in comparison of two decades. n indicates the numbers of bypass grafts. UV, Umbilical vein graft; pop, popliteal; BK, below-knee; AK, above-knee; AT, arterior tibial; PT, posterior tibial. Journal of Vascular Surgery 2002 35, 64-71DOI: (10.1067/mva.2002.121053) Copyright © 2002 Society for Vascular Surgery and The American Association for Vascular Surgery Terms and Conditions

Fig. 3 Indications for lower limb revascularization (1990 to 2000). Journal of Vascular Surgery 2002 35, 64-71DOI: (10.1067/mva.2002.121053) Copyright © 2002 Society for Vascular Surgery and The American Association for Vascular Surgery Terms and Conditions

Fig. 4 Comparative cumulative graft patency rates for popliteal reconstuctions with use of umbilical vein grafts during decades from 1975 to 1985 (bold lines) and from 1990 to 2000 (light lines and italics ). Difference in curves was statistically significant in comparison of decades with log-rank test (P <.05). UV, Umbilical vein graft; Pop, popliteal; SE, standard error. Journal of Vascular Surgery 2002 35, 64-71DOI: (10.1067/mva.2002.121053) Copyright © 2002 Society for Vascular Surgery and The American Association for Vascular Surgery Terms and Conditions

Fig. 5 Comparative cumulative graft patency rates for crural reconstuctions with use of umbilical vein graft during decades from 1975 to 1985 (bold lines) and from 1990 to 2000 (light lines and italics ). Differences between curves were statistically significant (P <.05). UV, Umbilical vein graft; SE, standard error. Journal of Vascular Surgery 2002 35, 64-71DOI: (10.1067/mva.2002.121053) Copyright © 2002 Society for Vascular Surgery and The American Association for Vascular Surgery Terms and Conditions

Fig. 6 Comparative cumulative limb salvage rates for popliteal and crural reconstuctions with use of umbilical vein graft during decades from 1975 to 1985 (bold lines) and from 1990 to 2000 (light lines and italics ). Differences between any curves were not statistically significant. UV, Umbilical vein graft; Pop, popliteal; SE, standard error. Journal of Vascular Surgery 2002 35, 64-71DOI: (10.1067/mva.2002.121053) Copyright © 2002 Society for Vascular Surgery and The American Association for Vascular Surgery Terms and Conditions