Model flow diagram. Model flow diagram. Rectangles represent mutually exclusive health states. Age-specific incidences are applied monthly to the susceptible.

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Model flow diagram. Model flow diagram. Rectangles represent mutually exclusive health states. Age-specific incidences are applied monthly to the susceptible population. Circles (sequelae and death) and small arrows (natural death) represent the proportion of the population removed from the model. Costs and benefits are computed monthly and aggregated over the cohort's lifetime. Non-consulting AOM episodes are accounted for in the quality of life calculation. AOM, acute otitis media; Sp, Streptococcus pneumoniae; TTP, tympanostomy tube placement. Emmanuelle Delgleize et al. BMJ Open 2016;6:e010776 ©2016 by British Medical Journal Publishing Group