Clinical and Translational Radiation Oncology

Slides:

Advertisements

Similar presentations

Dosimetric assessment of an Atlas based automated segmentation for loco-regional radiation therapy of early breast cancer in the Skagen Trial 1: A multi-institutional.

Advertisements

Automatic treatment planning improves the clinical quality of head and neck cancer treatment plans Christian Rønn Hansen, Anders Bertelsen, Irene Hazell,

Physics and Imaging in Radiation Oncology

Tumour-Targeted Treatment Intensification for Prostate Cancer Using Magnetic Resonance Imaging Guidance Jessy Abed, RTT, MHScMRS, Jenny Lee, MMath, Tim.

Abortion legislation: exploring perspectives of general practitioners and obstetrics and gynaecology clinicians Anastasia A. Theodosiou, Oliver R. Mitchell

Anastasia A. Theodosiou, Martin H. Johnson

Improved outcome of treating locally advanced lung cancer with the use of Lattice Radiotherapy (LRT): A case report Beatriz E. Amendola, Naipy C. Perez,

Evaluation of diffusion weighted imaging for tumor delineation in head-and-neck radiotherapy by comparison with automatically segmented 18F-fluorodeoxyglucose.

2-[18F]fluoro-2-deoxy-d-galactose positron emission tomography guided functional treatment planning of stereotactic body radiotherapy of liver tumours

2-[18F]fluoro-2-deoxy-d-galactose positron emission tomography guided functional treatment planning of stereotactic body radiotherapy of liver tumours

Automatic treatment planning improves the clinical quality of head and neck cancer treatment plans Christian Rønn Hansen, Anders Bertelsen, Irene Hazell,

Retrospective methods to estimate radiation dose at the site of breast cancer development after Hodgkin lymphoma radiotherapy Nicola S. Russell, Inge.

Radiotherapy dose-distribution to the perirectal fat space (PRS) is related to gastrointestinal control-related complications S.L. Gulliford, S. Ghose,

Pancreatic tumor motion reduction by use of a custom abdominal corset

Cortical stimulation parameters for functional mapping

Do protons and X-rays induce cell-killing in human peripheral blood lymphocytes by different mechanisms? J. Miszczyk, K. Rawojć, A. Panek, A. Borkowska,

Dosimetric Benefits and Practical Pitfalls of Daily Online Adaptive MRI-Guided Stereotactic Radiation Therapy for Pancreatic Cancer Nancy El-Bared, MD,

Retrospective assessment of MRI-based volumetric changes of normal tissues in glioma patients following radio(chemo)therapy Andreas Gommlich, Felix Raschke,

Physics and Imaging in Radiation Oncology

Physics and Imaging in Radiation Oncology

VMAT radiation-induced nausea and vomiting in adjuvant breast cancer radiotherapy: The incidental effect of low-dose bath exposure G. Lazzari, A. Terlizzi,

Resolution of atelectasis during radiochemotherapy of lung cancer with serious implications for further treatment. A case report Lore Helene Braun, Stefan.

Physics and Imaging in Radiation Oncology

Biosimilars to recombinant human FSH medicines: comparable efficacy and safety to the original biologic Fernando de Mora, Bart C.J.M. Fauser Reproductive.

Technical Innovations and Patient Support in Radiation Oncology

Axillary radiotherapy for nodal lymphoma: What CTV expansion is required to account for absence of pre-chemotherapy treatment position FDG PET-CT? Robin.

Physics and Imaging in Radiation Oncology

Potentials and challenges of diffusion-weighted magnetic resonance imaging in radiotherapy Sara Leibfarth, René M. Winter, Heidi Lyng, Daniel Zips, Daniela.

Clinical and Translational Radiation Oncology

Advantages of intensity modulated proton therapy during hippocampal avoidance whole brain radiation therapy Joshua Stoker, Sujay Vora, Ameet Patel, David.

Cone beam computed tomography-based monitoring and management of target and organ motion during external beam radiotherapy in cervical cancer Nina Boje.

Simultaneous integrated prophylactic cranial irradiation in sino-nasal cancer Kenneth Jensen, Maja Bendtsen Sharma, Simon Lenler-Eriksen, Per Friis, Anne.

Sequencing of the highly polymorphic STR locus SE33

Franziska Hauth, Mahmoud Toulany, Daniel Zips, Apostolos Menegakis

Efficacy of fiducial marker-based image-guided radiation therapy in prostate tomotherapy and potential dose coverage improvement using a patient positioning.

Volumetric modulated arc therapy based total body irradiation: Workflow and clinical experience with an indexed rotational immobilization system Luo.

Physics and Imaging in Radiation Oncology

Combined morphologic and metabolic pipeline for Positron emission tomography/computed tomography based radiotherapy response evaluation in locally advanced.

Cone-Beam CT-based position verification for oesophageal cancer: Evaluation of registration methods and anatomical changes during radiotherapy A. van.

Feasibility of stereotactic body radiotherapy for locally-advanced non-small cell lung cancer Katrina Woodford, Vanessa Panettieri, Trieumy Tran Le,

Technical Innovations and Patient Support in Radiation Oncology

Radiotherapy for isolated granulocytic sarcoma: Case report and review of literature Jose Antonio Dominguez Rullán, Eva Fernández Lizarbe, Belén Capuz,

Automated addition of Chelex solution to tubes containing trace items

Dosimetric assessment of an Atlas based automated segmentation for loco-regional radiation therapy of early breast cancer in the Skagen Trial 1: A multi-institutional.

Physics and Imaging in Radiation Oncology

Clinical and radiobiological evaluation of a method for planning target volume generation dependent on organ-at-risk exclusions in magnetic resonance.

Dose-per-Fraction Escalation of Accelerated Hypofractionated Three-Dimensional Conformal Radiotherapy in Locally Advanced Non-small Cell Lung Cancer

Uncertainty evaluation of image-based tumour control probability models in radiotherapy of prostate cancer using a visual analytic tool Oscar Casares-Magaz,

The posterior cerebellum, a new organ at risk?

Sites of recurrent disease and prognostic factors in SCLC patients treated with radiochemotherapy Rebecca Bütof, Calogero Gumina, Chiara Valentini, Antje.

Whole-ventricular irradiation for intracranial germ cell tumors: Dosimetric comparison of pencil beam scanned protons, intensity-modulated radiotherapy.

Design, fabrication, and validation of patient-specific electron tissue compensators for postmastectomy radiation therapy Daniel F. Craft, Peter Balter,

Rectal volume variations and estimated rectal dose during 8 weeks of image-guided radical 3D conformal external beam radiotherapy for prostate cancer

Cone beam CT based dose calculation in the thorax region

Colombian results of the interlaboratory quality control exercise 2015

Clinical and Translational Radiation Oncology

Individual lymph nodes: “See it and Zap it”

Clinical implementation of magnetic resonance imaging guided adaptive radiotherapy for localized prostate cancer Shyama U. Tetar, Anna M.E. Bruynzeel,

Technical Innovations and Patient Support in Radiation Oncology

Peter de Boer, Stefano Mandija, Anita M

The rationale for MR-only treatment planning for external radiotherapy

Technical Innovations and Patient Support in Radiation Oncology

Surface doses of flattening filter free beams with volumetric modulated arc therapy dose delivery for breast cancer Jan Seppälä, Aleksi Voutilainen,

R. Botman, S. U. Tetar, M. A. Palacios, B. J. Slotman, F. J

Beyond T2 and 3T: New MRI techniques for clinicians

Technical Innovations and Patient Support in Radiation Oncology

Probabilistic optimization of dose coverage in radiotherapy

Evaluation of plan adaptation strategies for stereotactic radiotherapy of lymph node oligometastases using online magnetic resonance image guidance Dennis.

Physics and Imaging in Radiation Oncology

Volumetric and dosimetric comparison of two delineation guidelines for the radiation treatment of laryngeal squamous cell carcinoma C. Bondue, S. Racadot,

Presentation transcript:

Clinical and Translational Radiation Oncology Comparison of the dose escalation potential for two hypofractionated radiotherapy regimens for locally advanced pancreatic cancer Jenny Bertholet, Arabella Hunt, Alex Dunlop, Thomas Bird, Robert A. Mitchell, Uwe Oelfke, Simeon Nill, Katharine Aitken Clinical and Translational Radiation Oncology Volume 16, Pages 21-27 (May 2019) DOI: 10.1016/j.ctro.2019.03.001 Copyright © 2019 The Authors Terms and Conditions

Fig. 1 Target coverage by the base (blue and red) and escalation (yellow) dose in 5 (top) or 15 (bottom) fractions. (Blue bars indicate the base plans. Red and yellow bars indicate dose escalation plans. Darker bars indicate the GTV and lighter bars indicate the PTV). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.) Clinical and Translational Radiation Oncology 2019 16, 21-27DOI: (10.1016/j.ctro.2019.03.001) Copyright © 2019 The Authors Terms and Conditions

Fig. 2 Dose distribution for the escalated plan in 5 fractions (top) and 15 fractions (bottom) for patient 5. Target coverage is equivalent in the 2 fractionation regimen. Clinical and Translational Radiation Oncology 2019 16, 21-27DOI: (10.1016/j.ctro.2019.03.001) Copyright © 2019 The Authors Terms and Conditions

Fig. 3 Potential for dose escalation in 5 (blue bars, equal to yellow bars in Fig. 1 top) and 15 (red bars, equal to yellow bars in Fig. 1 bottom) fractions with a BED≅100 Gy. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.) Clinical and Translational Radiation Oncology 2019 16, 21-27DOI: (10.1016/j.ctro.2019.03.001) Copyright © 2019 The Authors Terms and Conditions

Fig. 4 Dose distribution for the escalated dose plan in 5 fractions (top) and 15 fractions (bottom) for patient 2. PTV Coverage by the base dose (light green) is higher in 15 fractions (95%) than in 5 fractions (86%). However, PTV coverage by the escalated dose (dark red) is higher in 5 fraction (51%) than in 15 fraction (32%). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.) Clinical and Translational Radiation Oncology 2019 16, 21-27DOI: (10.1016/j.ctro.2019.03.001) Copyright © 2019 The Authors Terms and Conditions