Schematic diagram illustrating the distribution of postsynaptic receptors on an SPn for monosynaptic inputs arising from the thalamus (Thal.) and the CP,

Slides:



Advertisements
Similar presentations
1 The length constant of the dendritic tree markedly effects passive conduction.
Advertisements

Figure 8.1 Forms of short-term synaptic plasticity.
Lecture 14: The Biology of Learning References: H Shouval, M F Bear, L N Cooper, PNAS 99, (2002) H Shouval, G Castellani, B Blais, L C Yeung,
Long term potentiation (LTP) of an excitatory synaptic inputs is input specific.
Storage capacity: consider the neocortex ~20*10^9 cells, 20*10^13 synapses.
Action potential 1. Action potentials arriving at the presynaptic terminal cause voltage- gated Ca2+ channels to open. Ca Presynaptic terminal.
Postsynaptic Membrane Ion Channels ACh-R PhC a PIP 3 Dg PkC i a Endoplasmic Reticulum R NK1 c -R NK1 SP c -R NK1 -G R R ER IP 3 3 -R ER Pr PPhos + PhC.
Synaptic Transmission / Central Synapses I Tom O’Dell Department of Physiology C8-161 (NPI), x64654.
Synapses. C. Action potential reaches the end of a presynaptic neuron. F. Voltage gated calcium channels open D. Calcium ions flow into the presynaptic.
Long Term Potentiation
Comment on "On the Origin of Interictal Activity in Human Temporal Lobe Epilepsy in Vitro" by Christian Wozny, Anatol Kivi, Thomas-Nicolas Lehmann, Christoph.
Synaptic scaling in the developing visual cortex
Neurotransmitter Receptors
Modulating tonic inhibition regulates synaptic transmission at MF-PC and PF-PC synapses. Modulating tonic inhibition regulates synaptic transmission at.
1. An action potential arrives at the
Schematic representation of brain targets common to the neurobiology and pharmacology of epilepsy and aggression. Schematic representation of brain targets.
1. An action potential arrives at the
A Brief History of Long-Term Potentiation
Nat. Rev. Endocrinol. doi: /nrendo
Neuroscience of Addiction
Postsynaptic currents and potentials
Volume 32, Issue 3, Pages (November 2001)
Lecture 19 Synaptic transmission, vesicle fusion and cycling
P.P. De Deyn, R. Vanholder, R. D'Hooge
The BLA differentially targets CP neurons in PL and IL cortex.
A connectionist model in action
Model summarizing nicotinic effects on glutamate terminals in the DRN
Synaptic background activity.
Shox2+ neurons and two types of V2a (Chx10+) cells.
Huibert D Mansvelder, Daniel S McGehee  Neuron 
GABA Generates Excitement
From Cellular and Molecular Neurophysiology, Fourth Edition.
Repolarization of membrane potential is associated with a decreased membrane conductance. Repolarization of membrane potential is associated with a decreased.
Leptin-induced LTP at TA-CA1 synapses involves a postsynaptic expression mechanism. Leptin-induced LTP at TA-CA1 synapses involves a postsynaptic expression.
Proposed encoding of VLS MSNs
Schematic of the model of the visual motion pathway of the blowfly and the various modules from which it is composed. Schematic of the model of the visual.
Depolarization-induced postsynaptic NT secretion depends on Ca2+ influx. Depolarization-induced postsynaptic NT secretion depends on Ca2+ influx. Hippocampal.
Unaltered presynaptic transmitter secretion during pharmacological treatments. Unaltered presynaptic transmitter secretion during pharmacological treatments.
GABAA-TONIC receptor protein-IR did not vary between the dorsal and ventral SCN at any time point in either LD or DD (A–F). GABAA-TONIC receptor protein-IR.
David C. Spanswick, Stephanie E. Simonds, Michael A. Cowley 
Increased phosphorylation of Akt, Girdin S1416, and NR2B of NMDA receptor in the hippocampus of mouse after fear conditioning. Increased phosphorylation.
Changes in the extent of swim recovery correlated with polysynaptic actions. Changes in the extent of swim recovery correlated with polysynaptic actions.
Double immunostaining of P2X7R and cell-specific markers in morphine-tolerated rats. Double immunostaining of P2X7R and cell-specific markers in morphine-tolerated.
A schematic diagram illustrating the arrival of axons onto layer III neurons during normal development (top). A schematic diagram illustrating the arrival.
Hsp70 protected against iAβ toxicity by increasing proteasomal activity. Hsp70 protected against iAβ toxicity by increasing proteasomal activity. A–C,
Spike timing-dependent plasticity
Spontaneous EPSC and IPSC dynamics in 3 mm and 1 mm Ca2+.
Physiological characteristics of large fastigial glycinergic neurons resemble those of large glutamatergic neurons, not small glycinergic neurons. a, Action.
Estradiol but not progesterone increases overall excitability and burst events in AVPV kisspeptin neurons. Estradiol but not progesterone increases overall.
Diagram depicting the location of electrode placement.
A schematic summary depicting the effects of CIE exposure on the intrinsic and synaptic actions of DA receptors on pyramidal neurons and FS interneurons.
Rapid Neocortical Dynamics: Cellular and Network Mechanisms
Light illumination activates primary afferents with conduction velocity in a range of Aβ fibers. Light illumination activates primary afferents with conduction.
Schematic illustration summarizing the effect of orthopedic mice surgery on hippocampal astrocyte-neuron metabolism, structure, and function. Schematic.
Leptin-induced LTP involves a PI 3-kinase-dependent process.
Sox11 and Sox4 are dynamically expressed during corticogenesis in overlapping and discrete cellular populations. Sox11 and Sox4 are dynamically expressed.
BACHD mice demonstrate decreases in synaptic activity of medium-sized spiny neurons at 6 months. BACHD mice demonstrate decreases in synaptic activity.
Depolarization-evoked firing activity of hippocampal bipolar neurons that have been dissociated from F344/NSlc and Hiss rats. Depolarization-evoked firing.
PSCs elicited by electrical stimulation of the subplate.
A proposed scheme for GSK-3-involved suppression of synaptic transmission. A proposed scheme for GSK-3-involved suppression of synaptic transmission. According.
E-stimulation of the olfactory nerve evokes PGC inhibitory responses in distant glomeruli. E-stimulation of the olfactory nerve evokes PGC inhibitory responses.
PdN6 disconnection impairs synaptic actions of C2 onto VSI
Rate of current rundown through VDCC and NMDA receptor channels is reduced in gelsolin-deficient hippocampal neurons. Rate of current rundown through VDCC.
Shank3 homozygous mice exibited impairment in synaptic transmission, induction, and maintenance of long-term potentiation. Shank3 homozygous mice exibited.
Schematic diagram of the mechanisms underlying astrocyte-mediated brain ischemic tolerance. Schematic diagram of the mechanisms underlying astrocyte-mediated.
BIOL3833 Week 11b: Dendrites.
Nonlinear transfer of signal and noise correlations in vivo.
Target-specific DSI at TRN synapses.
Depression of NMDA receptor-mediated EPSCs
The effect of roscovitine on Ca2+-dependent glutamate release from synaptosomes prepared from rat brains in response to membrane depolarization with 1.
Presentation transcript:

Schematic diagram illustrating the distribution of postsynaptic receptors on an SPn for monosynaptic inputs arising from the thalamus (Thal.) and the CP, including layers V and VI, and within the SP. Note that only synaptic inputs from other SPn can lead to... Schematic diagram illustrating the distribution of postsynaptic receptors on an SPn for monosynaptic inputs arising from the thalamus (Thal.) and the CP, including layers V and VI, and within the SP. Note that only synaptic inputs from other SPn can lead to activation of depolarizing GABAA receptors and NMDA receptors at negative membrane potentials. Ileana L. Hanganu et al. J. Neurosci. 2002;22:7165-7176 ©2002 by Society for Neuroscience