Table 1. Histological disease score

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Table 1. Histological disease score Grade 0 Normal colonic mucosa Grade 1 Loss of one-third of the crypts Grade 2 Loss of two-thirds of the crypts Grade 3 The lamina propria is covered with a single layer of epithelium and mild inflammatory cell infiltration is present Grade 4 Erosions and marked inflammatory cell infiltration are present Randomly selected 8 fields (magnified 100 times) in each section were inspected and graded as above by a pathologist who was blinded to the treatment protocol. The mean in each section was calculated by scoring the grades in 8 fields. Ahmed M. Kabel et al. Effect of Indole-3-carbinol and/or Metformin on Female Patients with Ulcerative Colitis (Premalignant Condition): Role of Oxidative Stress, Apoptosis and Proinflammatory Cytokines. Journal of Cancer Research and Treatment, 2017, Vol. 5, No. 1, 1-8. doi:10.12691/jcrt-5-1-1 © The Author(s) 2015. Published by Science and Education Publishing.