Wild-type but not OMP−/− pups prefer the biological mother.

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Wild-type but not OMP−/− pups prefer the biological mother. Wild-type but not OMP−/− pups prefer the biological mother. A, B, WT pups preferred to suckle or huddle with the biological mother over another unfamiliar lactating female (A), while OMP−/− mice failed to show preference (B). The nose of each pup is marked by a dot and its location relative to the midline (dashed line) between the two anesthetized mothers is used to assign the pup's preference. C, Summary of mother preference for WT and OMP−/− pups. The numbers in parentheses indicate the total number of pups tested in each group. Statistical analysis was performed using a χ2 test. The choice between a lactating and a nonlactating female (both are unfamiliar) was tested from two litters of each genotype. Anderson C. Lee et al. J. Neurosci. 2011;31:2974-2982 ©2011 by Society for Neuroscience