Day 3 morphology is a poor predictor of blastocyst quality in extended culture  James Graham, M.S., Taer Han, B.S., Richard Porter, Michael Levy, M.D.,

Slides:



Advertisements
Similar presentations
Pregnancy rates after embryo transfer depend on the provider at embryo transfer22 Rhonda M Hearns-Stokes, M.D., Bradley T Miller, M.D., Lynette Scott,
Advertisements

Early-stage endometriosis: adhesion and growth of human menstrual endometrium in nude mice Michelle Nisolle, M.D., Ph.D., Françoise Casanas-Roux, B.S.,
Human blastocyst morphological quality is significantly improved in embryos classified as fast on day 3 (≥10 cells), bringing into question current embryological.
Is the effect of premature elevated progesterone augmented by human chorionic gonadotropin versus gonadotropin-releasing hormone agonist trigger?  Matthew.
Evaluation of basal estradiol levels in assisted reproductive technology cycles2  John L Frattarelli, M.D., Paul A Bergh, M.D., Michael R Drews, M.D.,
It’s time to pay attention to the endometrium
The value of fast blastocoele re-expansion in the selection of a viable thawed blastocyst for transfer  Yimin Shu, M.D., Ph.D., Jill Watt, Ph.D., Janice.
Patient and cycle characteristics predicting high pregnancy rates with single-embryo transfer: an analysis of the Society for Assisted Reproductive Technology.
Anil K Dubey, Ph. D. , Jose R Cruz, M. D. , Beth Hartog, M. D
Contrasting patterns in in vitro fertilization pregnancy rates among fresh autologous, fresh oocyte donor, and cryopreserved cycles with the use of day.
Trophectoderm grade predicts outcomes of single-blastocyst transfers
Seasonal variations and age-related changes in human sperm count, motility, motion parameters, morphology, and white blood cell concentration  Grace M.
Can an educational DVD improve the acceptability of elective single embryo transfer? A randomized controlled study  Nicole Hope, M.B., B.S., Hon., Luk.
Culture Matters: Direct Service Programs Cannot Solve Widespread, Complex, Intergenerational Social Problems. Culture Change Can  Laura Porter, Kim Martin,
Recombinant human leukemia inhibitory factor enhances the development of preimplantation mouse embryo in vitro  Horng-Der Tsai, M.D., Chi-Chen Chang,
Differences in in vitro fertilization (IVF) outcome between white and black women in an inner-city, university-based IVF program  Fady I Sharara, M.D.,
Factors associated with birth outcomes from cryopreserved blastocysts: experience from 4,597 autologous transfers of 7,597 cryopreserved blastocysts 
Dramatic declines in implantation and pregnancy rates in patients who undergo repeated cycles of in vitro fertilization with blastocyst transfer after.
Craig A. H Richard, Ph. D. , Carolyn J Kubik, M. D
Examining the temperature of embryo culture in in vitro fertilization: a randomized controlled trial comparing traditional core temperature (37°C) to.
Clinical experience and perinatal outcome of blastocyst transfer after coculture of human embryos with human endometrial epithelial cells: a 5-year follow-up.
In vitro blastocyst formation of human oocytes obtained from unstimulated and stimulated cycles after vitrification at various maturational stages  Hyung.
Increase of success rate for women undergoing embryo transfer by transcutaneous electrical acupoint stimulation: a prospective randomized placebo-controlled.
Modified natural cycle in in vitro fertilization
Predictive value of embryo grading for embryos with known outcomes
Multinucleation in normally fertilized embryos is associated with an accelerated ovulation induction response and lower implantation and pregnancy rates.
Moving to blastocyst biopsy for preimplantation genetic diagnosis and single embryo transfer at sydney IVF  Kylie A de Boer, Ph.D., James W Catt, Ph.D.,
Robert G Brzyski, M. D. , Ph. D. , Peter A Binkley, B. S. , J
Is oocyte meiotic spindle morphology associated with embryo ploidy
Remembering Gary D. Hodgen, Ph.D.: 1943–2005
Initial IVF-ET experience with assisted hatching performed 3 days after retrieval followed by day 5 embryo transfer  Margaret C. Graham, M.S., Kathleen.
Dmitry M. Kissin, M. D. , M. P. H. , Jennifer F. Kawwass, M. D
Human chorionic gonadotropin levels after blastocyst transfer are highly predictive of pregnancy outcome1  Theocharis C Papageorgiou, M.D., Mark P Leondires,
Noninvasive metabolomic profiling of human embryo culture media using Raman spectroscopy predicts embryonic reproductive potential: a prospective blinded.
Fewer than 9 days of estrogen exposure prior to progesterone initiation results in lower pregnancy rates in programmed frozen embryo transfer cycles 
Executive summary: stages of reproductive aging workshop (STRAW)
Clomiphene citrate at 50: the dawning of assisted reproduction
Using the Society for Assisted Reproductive Technology Clinic Outcome System morphological measures to predict live birth after assisted reproductive.
Hydrosalpinx fluid affects murine embryonic development in a coculture system with epithelial endometrial cells  Isabel Carrasco, Elisa Cebral, Ph.D.,
Normal birth after single-embryo transfer in a patient with excessive polypronuclear zygote formation following in vitro fertilization and intracytoplasmic.
Does a frozen embryo transfer ameliorate the effect of elevated progesterone seen in fresh transfer cycles?  Mae Wu Healy, D.O., George Patounakis, M.D.,
Should embryos developing to blastocysts on day 7 be cryopreserved and transferred: an analysis of pregnancy and implantation rates  George Kovalevsky,
Cleavage-stage biopsy significantly impairs human embryonic implantation potential while blastocyst biopsy does not: a randomized and paired clinical.
Frequency and effect of vaginal bleeding on pregnancy outcome during the first 3 weeks after positive β-hCG test results following IVF-ET  Glen E Hofmann,
Samer Alfarawati, M. S. , Elpida Fragouli, Ph. D. , Pere Colls, Ph. D
Laura Detti, M. D. , Rebecca A. Uhlmann, M. S. , Nicole M. Fletcher, B
Nitric oxide metabolite production in the human preimplantation embryo and successful blastocyst formation  Christopher W. Lipari, M.D., Jairo E. Garcia,
Oocyte vitrification does not increase the risk of embryonic aneuploidy or diminish the implantation potential of blastocysts created after intracytoplasmic.
Successful elective and medically indicated oocyte vitrification and warming for autologous in vitro fertilization, with predicted birth probabilities.
Lysed cell removal promotes frozen–thawed embryo development
Aaron K. Styer, M. D. , Diane L. Wright, Ph. D. , H. C. L. D. , Anne M
Human embryo twinning with applications in reproductive medicine
Noha H Farag, M. D. , Scott C Matthews, M. D. , Eva Brzezinski, M. S
Dizygotic twin delivery following in vitro fertilization and transfer of thawed blastocysts cryopreserved at day 6 and 7  E.Scott Sills, M.D., Cindy L.
Effects of different laser-drilled openings in the zona pellucida on hatching of in vitro– produced cattle blastocysts  Friedrich Schmoll, Ph.D., Hendrik.
Regulation of assisted reproductive technologies in the United States
Temporal and morphologic characteristics of pinopod expression across the secretory phase of the endometrial cycle in normally cycling women with proven.
Koji Matsuura, Ph. D. , Nobuyoshi Hayashi, M. D. , Ph. D
Comprehensive chromosome screening is highly predictive of the reproductive potential of human embryos: a prospective, blinded, nonselection study  Richard.
Barry Behr, Ph.D., H.C.L.D., Amin A Milki, M.D. 
Reduction of postoperative adhesions by N,O-carboxymethylchitosan: a pilot study  Michael P Diamond, M.D., Anthony Luciano, M.D., D.Alan Johns, M.D., Randall.
Assessing the reproductive competence of individual embryos: a proposal for the validation of new “-omics” technologies  Richard T. Scott, M.D., H.C.L.D.,
Blastocyst biopsy with comprehensive chromosome screening and fresh embryo transfer significantly increases in vitro fertilization implantation and delivery.
David H. Barad, M.D., M.S., Norbert Gleicher, M.D. 
Experience with a patient-friendly, mandatory, single-blastocyst transfer policy: the power of one  John M. Csokmay, M.D., Micah J. Hill, D.O., Rebecca.
William B Schoolcraft, M.D., David K Gardner  Fertility and Sterility 
Comprehensive chromosome screening alters traditional morphology-based embryo selection: a prospective study of 100 consecutive cycles of planned fresh.
Peter M. Martin, M.D., H.Gilbert Welch, M.D.  Fertility and Sterility 
Potential risk of monochorionic dizygotic twin blastocyst formation associated with early laser zona dissection of group cultured embryos  Mitchel C.
Nathan R. Treff, Ph. D. , Jessyca Campos, M. S. , Xin Tao, M. S
Presentation transcript:

Day 3 morphology is a poor predictor of blastocyst quality in extended culture  James Graham, M.S., Taer Han, B.S., Richard Porter, Michael Levy, M.D., Robert Stillman, M.D., Michael J Tucker, Ph.D.  Fertility and Sterility  Volume 74, Issue 3, Pages 495-497 (September 2000) DOI: 10.1016/S0015-0282(00)00689-0

Figure 1 Predicted embryo use on day 3 compared with actual use on day 5/6. Black bars indicate embryos that would have been selected on day 3; white bars indicate embryos selected on day 5/6 that were not selected on day 3. Graham. Day 3 morphology is a poor predictor. Fertil Steril 2000. Fertility and Sterility 2000 74, 495-497DOI: (10.1016/S0015-0282(00)00689-0)