Evaluation and Medical Management of Erectile Dysfunction

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Evaluation and Medical Management of Erectile Dysfunction Thomas J. Beckman, MD, Haitham S. Abu-Lebdeh, MD, Lance A. Mynderse, MD Mayo Clinic Proceedings Volume 81, Issue 3, Pages 385-390 (March 2006) DOI: 10.4065/81.3.385 Copyright © 2006 Mayo Foundation for Medical Education and Research Terms and Conditions

FIGURE 1 Mechanism for penile erection and the molecular activity of PDE-5 inhibitors. Nitric oxide is released from nonadrenergic/noncholinergic nerve terminals and endothelial cells in the corpus cavernosum. cGMP = cyclic guanosine monophosphate; GTP = guanosine triphosphate; PDE-5 = phosphodiesterase type 5. Mayo Clinic Proceedings 2006 81, 385-390DOI: (10.4065/81.3.385) Copyright © 2006 Mayo Foundation for Medical Education and Research Terms and Conditions