STARmap for 3D transcriptome imaging and molecular cell typing.

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Demonstrations I, II, and III.

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Presentation transcript:

STARmap for 3D transcriptome imaging and molecular cell typing. STARmap for 3D transcriptome imaging and molecular cell typing. STARmap is an in situ RNA-sequencing technology that transforms intact tissue into a 3D hydrogel-tissue hybrid and measures spatially resolved single-cell transcriptomes in situ. Error- and background-reduction mechanisms are implemented at multiple layers, enabling precise RNA quantification, spatially resolved cell typing, scalability to large gene numbers, and 3D mapping of tissue architecture. Xiao Wang et al. Science 2018;361:eaat5691 Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works