Cumulative live birth rates in cohorts of patients treated with in vitro fertilization or intracytoplasmic sperm injection Cynthia Witsenburg, M.D.,

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Presentation transcript:

Cumulative live birth rates in cohorts of patients treated with in vitro fertilization or intracytoplasmic sperm injection Cynthia Witsenburg, M.D., Sandra Dieben, M.D., Lucette Van der Westerlaken, M.Sc., Harjo Verburg, M.D., Nico Naaktgeboren, Ph.D. Fertility and Sterility Volume 84, Issue 1, Pages 99-107 (July 2005) DOI: 10.1016/j.fertnstert.2005.02.013 Copyright © 2005 American Society for Reproductive Medicine Terms and Conditions

FIGURE 1 Cumulative live birth and dropout rate after IVF/ICSI as function of treatment cycle number. The live births are subdivided into singletons in the black bands, twin births in blue bands, and triplet births in yellow bands. Patients continuing treatment are in gray bands and patients that stopped further treatment are in red bands. Witsenburg. Cohort follow-up of IVF/ICSI patients. Fertil Steril 2005. Fertility and Sterility 2005 84, 99-107DOI: (10.1016/j.fertnstert.2005.02.013) Copyright © 2005 American Society for Reproductive Medicine Terms and Conditions

FIGURE 2 Relation of cumulative dropout rate after 2 treatment cycles and observed cumulative success rate. The letters B–I correspond to the references as indicated in Table 5; A = the data from this study. Witsenburg. Cohort follow-up of IVF/ICSI patients. Fertil Steril 2005. Fertility and Sterility 2005 84, 99-107DOI: (10.1016/j.fertnstert.2005.02.013) Copyright © 2005 American Society for Reproductive Medicine Terms and Conditions

FIGURE 3 Live birth rate per cycle (light blue bars) and cumulative live birth rate per patient (dark blue bars) for the LUMC cohort and the “transport clinic” cohort. a Results are significantly different (P<.001). Witsenburg. Cohort follow-up of IVF/ICSI patients. Fertil Steril 2005. Fertility and Sterility 2005 84, 99-107DOI: (10.1016/j.fertnstert.2005.02.013) Copyright © 2005 American Society for Reproductive Medicine Terms and Conditions

FIGURE 4 Relation of the observed cumulative live birth rate and the overestimation factor. Results after a follow-up period of 3 cycles are shown by the red line; a follow-up of 5 or more cycles is represented by the blue line. Data points refer to Table 5. A = the data from this study. Witsenburg. Cohort follow-up of IVF/ICSI patients. Fertil Steril 2005. Fertility and Sterility 2005 84, 99-107DOI: (10.1016/j.fertnstert.2005.02.013) Copyright © 2005 American Society for Reproductive Medicine Terms and Conditions