Glutamate responses are enhanced by coapplication of IMP, consistent with umami taste stimulation. Glutamate responses are enhanced by coapplication of.

Slides:

Advertisements

Similar presentations

Paradigm of Ideas on the Existence of Variation in Human Umami Taste Perception

Advertisements

The reading is 7.38 mm. The reading is 7.72 mm.

Effect of N-WASp glutathione-S-transferase (GST) fusion proteins on force in tracheal muscle strips stimulated with 10−5 M ACh under isometric conditions.

Extracellular Ca2+ influx is essential but not sufficient for BCR‐mediated SRF activation in WT DT40 cells. Extracellular Ca2+ influx is essential but.

Supplemental Fig 2. Wu et al

Mechanism of stabilization of the closed conformation of the umami receptor VFTM by IMP (green). Mechanism of stabilization of the closed conformation.

A Kainate Receptor Increases the Efficacy of GABAergic Synapses

The histamine-cytokine network in allergic inflammation

Jill S Cameron, Loic Lhuillier, Priya Subramony, Stuart E Dryer Neuron

PmCo feedback enhances MC responses to vomeronasal inputs.

Incidence and spatial extent of epileptiform events observed in widefield calcium imaging. Incidence and spatial extent of epileptiform events observed.

Plasticity of Burst Firing Induced by Synergistic Activation of Metabotropic Glutamate and Acetylcholine Receptors Shannon J. Moore, Donald C. Cooper,

Image processing and computer vision pipeline for segmentation and cell detection. Image processing and computer vision pipeline for segmentation and cell.

Current Injection Provokes Rapid Expansion of the Guard Cell Cytosolic Volume and Triggers Ca2+ Signals Lena J. Voss, Rainer Hedrich, M. Rob G. Roelfsema

Characteristics of the Camphor-Off switch.

Figure 3 ADP-evoked intracellular calcium responses discriminate between human microglia and macrophages while increased ADP-evoked intracellular calcium.

Intracellular injection of apSyn enhances evoked neurotransmitter release from C1 neuron somata cultured under low-release conditions. Intracellular injection.

Involvement of IRS-1 in L-783,281–stimulated increases in [Ca2+]i and exocytosis. Involvement of IRS-1 in L-783,281–stimulated increases in [Ca2+]i and.

LSPS in the presence of 200 µM caged-glutamate.

Depolarization-induced postsynaptic NT secretion depends on Ca2+ influx. Depolarization-induced postsynaptic NT secretion depends on Ca2+ influx. Hippocampal.

Selective modulation of AMPAR-mediated transmission in 4E-BP2−/− mice.

Kv2. 1-like currents are related linearly to estimates of Kv2

CX3CR1 deficiency impairs the functional maturation of thalamocortical synapses. CX3CR1 deficiency impairs the functional maturation of thalamocortical.

Relationship between hippocampal volume and the number of reported episodic and nonepisodic details. Relationship between hippocampal volume and the number.

The lack of effect of denatonium to stimulate insulin release in the absence of extracellular Ca2+ or in the presence of 10 μmol/l nitrendipine. The lack.

Bicuculline-sensitive current sharpened the frequency response.

Relationship between spiking and 5K signal in vivo.

Kinetics of Synaptic Vesicle Refilling with Neurotransmitter Glutamate

Ih activation is required for sigh but not for eupnea generation.

Application of GABA to nucleated patches from dentate granule cells induces SR95531-sensitive channel openings. Application of GABA to nucleated patches.

Chronic SSRI treatment rescued lOFC hyperactivity in QNP-treated mice.

Effect of IBMP and PKG on cAMP levels

HIF-1 is required for IGF-1-induced VEGF mRNA expression and protein secretion. HIF-1 is required for IGF-1-induced VEGF mRNA expression and protein secretion.

Spontaneous EPSC and IPSC dynamics in 3 mm and 1 mm Ca2+.

Pyknosis in the RGC layer.

Analysis of potential contribution of spike timing to plasticity.

Disrupted Ca2+ homeostasis enhances wild-type TDP-43 toxicity.

Ca2+-dependent recovery does not contribute to steady-state transmission. Ca2+-dependent recovery does not contribute to steady-state transmission. A,

PreBötC activity in low [K+]o implicates neuronal activity from both subpopulations. PreBötC activity in low [K+]o implicates neuronal activity from both.

Alexandre Mathy, Beverley A. Clark, Michael Häusser Neuron

An ERK-signaling process underlies HFS-induced LTP at TA-CA1 synapses.

Effects of an AMPA receptor antagonist on numbers of pCofilin-positive spines. Effects of an AMPA receptor antagonist on numbers of pCofilin-positive spines.

Two-pool depletion model predicts frequency-dependent synaptic depression at cartwheel cell synapse. Two-pool depletion model predicts frequency-dependent.

Depolarization-evoked firing activity of hippocampal bipolar neurons that have been dissociated from F344/NSlc and Hiss rats. Depolarization-evoked firing.

Activation of microglial group III mGlu receptors inhibits the release of soluble, stable neurotoxins. Activation of microglial group III mGlu receptors.

GABA and corticosterone selectively affect the activity of NE- and KCl-responsive precursor cells. GABA and corticosterone selectively affect the activity.

Taste cell responses (ΔCa2+) evoked by umami and salty taste stimuli, recorded in a slice preparation of the mouse circumvallate papilla. Taste cell responses.

HFD increased the number of ERα-expressing cells.

L-AP-4 depressed local synaptic glutamate release in the lateral hypothalamus. l-AP-4 depressed local synaptic glutamate release in the lateral hypothalamus.

Potentiation of proton-gated current in CHO cells expressing ASICs

Electrical stimulation of septohippocampal fibers induced fast-onset glutamatergic responses in CA3 pyramidal cells. Electrical stimulation of septohippocampal.

SSC LTP in narrow-field vertical neurons is induced by SO stimulation at 20 Hz for 20 s. sSC LTP in narrow-field vertical neurons is induced by SO stimulation.

ROS generation at reoxygenation is attributable to NADPH oxidase and is calcium dependent. ROS generation at reoxygenation is attributable to NADPH oxidase.

Absence of PC-induced ischemic tolerance in P2X7−/− mice.

Effects of receptor antagonists, Ca2+ channel blocker, Ca2+depletion, and protein kinase inhibitors on CREB phosphorylation in cultured hippocampal neurons.

Rate of current rundown through VDCC and NMDA receptor channels is reduced in gelsolin-deficient hippocampal neurons. Rate of current rundown through VDCC.

PNU enhances Ca2+ flux mediated by an engineered variant of the human α7 nAChR. PNU enhances Ca2+ flux mediated by an engineered variant.

Acute applications display only slight pharmacological differences among menthol stereoisomers. Acute applications display only slight pharmacological.

SLC30A10 protects DAergic neurons from neurodegeneration induced by Mn exposure. SLC30A10 protects DAergic neurons from neurodegeneration induced by Mn.

Cytotoxic activity of CD8+ T-cells stimulated with SSX2-derived p

Summary of the antagonistic effects of CPPG

A, Representative voltage-clamp recordings from a CRF1+ neuron during superfusion of GBZ (100 μm), followed by PTX (100 μm, top trace) and during superfusion.

Effect of IS on proliferation, senescence, and the production of NO and ROS from endothelial cells. Effect of IS on proliferation, senescence, and the.

Enhanced expression of Cap43 gene by nickel in breast cancer cell lines. Enhanced expression of Cap43 gene by nickel in breast cancer cell lines. Expression.

Effect of MIF siRNA on the production of MMP-13 induced by LPA

Long-lived antibody-secreting cells in the bone marrow, induced by PfCelTOS vaccines containing various adjuvant formulations with emulsion doses of 0.02%

Long-lived antibody-secreting cells in the bone marrow, induced by PfCelTOS vaccines containing various adjuvant formulations with emulsion doses of 0.5%

BDNF protein is expressed in neurons and astrocytes of hippocampus after pilocarpine-induced SE. A, Representative confocal images of hippocampal subfields.

The effect of roscovitine on Ca2+-dependent glutamate release from synaptosomes prepared from rat brains in response to membrane depolarization with 1.

The DOR agonist DPDPE evokes and occludes I-LTD.

Presentation transcript:

Glutamate responses are enhanced by coapplication of IMP, consistent with umami taste stimulation. Glutamate responses are enhanced by coapplication of IMP, consistent with umami taste stimulation. A, Responses evoked by MPG (30 mm) were enhanced by coapplication of IMP (1 mm). IMP alone did not induce a detectable Ca2+ response (middle trace). B, Concentration–response relationship for glutamate in the presence (filled circles) or absence (open circles) of 1 mm IMP (means ± SE; n = 4 cells)‏ Yutaka Maruyama et al. J. Neurosci. 2006;26:2227-2234 ©2006 by Society for Neuroscience