Volume 65, Issue 2, Pages (February 2004)

Slides:

Advertisements

Similar presentations

Myoung J. Kang, Alistair Ingram, Hao Ly, Kerri Thai, James W. Scholey

Advertisements

The overdriven glomerulus as a cardiovascular risk factor

Plasma sodium and hypertension

Low protein diet mediated renoprotection in remnant kidneys: Renal autoregulatory versus hypertrophic mechanisms Karen A. Griffin, Maria Picken, Anita.

Hydroxyethyl starch and change in renal function in patients undergoing coronary artery bypass graft surgery Wolfgang C. Winkelmayer, Robert J. Glynn,

Volume 58, Issue 1, Pages (July 2000)

Lack of evidence of blood pressure-independent protection by renin-angiotensin system blockade after renal ablation Anil K. Bidani, M.D., Karen A. Griffin,

Robert W. Schrier, Kimberly K. McFann, Ann M. Johnson

Prenatal exposure to nicotine modifies kidney weight and blood pressure in genetically susceptible rats: A case of gene-environment interaction Zdenka.

Glomerulus number and blood pressure in the Prague hypertensive rat

Prehypertension and chronic kidney disease: the ox or the plow?

Progression of renal failure and hypertensive nephrosclerosis

John P. Middleton, Patrick H. Pun Kidney International

Volume 77, Issue 1, Pages 6-8 (January 2010)

The overdriven glomerulus as a cardiovascular risk factor

The myogenic response in uremic hypertension

Peripheral microvascular parameters in the nephrotic syndrome

Comorbidity and confounding in end-stage renal disease

Volume 81, Issue 3, Pages (February 2012)

Volume 70, Issue 11, Pages (December 2006)

Volume 87, Issue 2, Pages (February 2015)

Impaired response of the denervated kidney to endothelin receptor blockade in normotensive and spontaneously hypertensive rats Radoslav Girchev, Angela.

Up-regulation of kidney NAD(P)H oxidase and calcineurin in SHR: Reversal by lifelong antioxidant supplementation Chang-de Zhan, Ram K. Sindhu, Nosratola.

Prospective randomized study of individual and group psychotherapy versus controls in recipients of renal transplants1 Lyndsay S. Baines, John T. Joseph,

Volume 70, Issue 12, Pages (December 2006)

Julia E. Tank, Orson W. Moe, William L. Henrich Kidney International

James D. House, Margaret E. Brosnan, John T. Brosnan

Blood pressure targets in hemodialysis patients

Volume 56, Issue 4, Pages (October 1999)

Structure, not just function

Volume 55, Issue 2, Pages (February 1999)

Hypertension, race, and glomeruli: more than simply a numbers game

Volume 58, Issue 1, Pages (July 2000)

The third World Kidney Day: Looking back and thinking forward

Volume 61, Issue 6, Pages (June 2002)

Volume 69, Issue 12, Pages (June 2006)

Volume 69, Issue 3, Pages (February 2006)

Volume 63, Pages S38-S42 (February 2003)

Volume 62, Issue 3, Pages (September 2002)

Role of endothelin and nitric oxide imbalance in the pathogenesis of hypoxia-induced arterial hypertension Zhenmin Ni, Shahrooz Bemanian, Salah D. Kivlighn,

Volume 61, Issue 1, Pages (January 2002)

Volume 68, Issue 4, Pages (October 2005)

Neurogenic factors and hypertension in renal disease

Michael W. Steffes, Derek Schmidt, Rebecca Mccrery, John M. Basgen

Volume 56, Issue 5, Pages (November 1999)

Volume 81, Issue 4, Pages (February 2012)

Volume 54, Pages S135-S139 (December 1998)

Circadian regulation of renal function

Determinants of glomerular hypofiltration in aging humans

Volume 64, Issue 2, Pages (August 2003)

Volume 63, Issue 1, Pages (January 2003)

The course of the remnant kidney model in mice

Aldosterone in the development and progression of renal injury

Volume 63, Issue 4, Pages (April 2003)

Atherosclerotic renal artery stenosis and reconstruction

Volume 68, Issue 5, Pages (November 2005)

American Indian heritage and risk factors for renal injury

Is it the low-protein diet or simply the salt restriction?

Volume 59, Issue 5, Pages (May 2001)

Importance of blood pressure control in hemodialysis patient survival

Volume 68, Issue 1, Pages (July 2005)

Volume 65, Issue 1, Pages (January 2004)

Volume 56, Issue 2, Pages (August 1999)

Volume 54, Pages S207-S210 (September 1998)

Volume 58, Issue 2, Pages (August 2000)

Effect of prenatal dexamethasone on rat renal development

Volume 61, Issue 1, Pages (January 2002)

Wendy E. Hoy, Megan Rees, Emma Kile, John D. Mathews, Zhiqiang Wang

Structural remodeling of resistance arteries in uremic hypertension

Volume 62, Pages S2-S7 (December 2002)

Presentation transcript:

Volume 65, Issue 2, Pages 582-588 (February 2004) Is there an association between level of adult blood pressure and nephron number or renal filtration surface area? M. Jane Black, Todd A. Briscoe, Marios Constantinou, Michelle M. Kett, John F. Bertram Kidney International Volume 65, Issue 2, Pages 582-588 (February 2004) DOI: 10.1111/j.1523-1755.2004.00406.x Copyright © 2004 International Society of Nephrology Terms and Conditions

Figure 1 Tail-cuff systolic blood pressure from 10 to 15weeks of age in male spontaneously hypertensive rats (SHR)(N = 8)and Wistar-Kyoto (WKY) rats(N = 8), and from 6 to 16weeks of age in F1 offspring(N = 8). Values are means ± SEM. Kidney International 2004 65, 582-588DOI: (10.1111/j.1523-1755.2004.00406.x) Copyright © 2004 International Society of Nephrology Terms and Conditions

Figure 2 Measurements of pressure from 5 to 15weeks of age in F2 male rats. (A) Tail-cuff systolic blood pressure from 5 to 15weeks of age in F2 male rats (N = 17). Values are means with minimum and maximum values for each time point. (B) Scatter plot of mean arterial pressures at 15weeks of age in F2 rats. Kidney International 2004 65, 582-588DOI: (10.1111/j.1523-1755.2004.00406.x) Copyright © 2004 International Society of Nephrology Terms and Conditions

Figure 3 Glomeruli of F2 male rats at 15weeks of age. (A) Scatter plot of the total number of glomeruli in the kidneys of F2 male rats (N = 17) at 15weeks of age. (B) Linear regression analysis of the total number of glomeruli per kidney versus mean arterial pressure in the F2 male rats at 15weeks of age. (C) Linear regression analysis of the number of glomeruli per kidney versus volume of an average glomerulus in the F2 male rats at 15weeks of age. Kidney International 2004 65, 582-588DOI: (10.1111/j.1523-1755.2004.00406.x) Copyright © 2004 International Society of Nephrology Terms and Conditions

Figure 4 Total renal filtration surface area in the F2 rats at 15weeks of age. (A) Scatter plot of the total renal filtration surface area in the F2 rats (N = 17) at 15weeks of age. (B) Linear regression analysis of the total renal filtration surface area versus the mean arterial pressure in the F2 rats at 15weeks of age. Kidney International 2004 65, 582-588DOI: (10.1111/j.1523-1755.2004.00406.x) Copyright © 2004 International Society of Nephrology Terms and Conditions