The authors have no financial interest

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OCT= Optical Coherence Tomography

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Presentation transcript:

The authors have no financial interest Emory University Analysis of Thin Microkeratome Flap Architecture Using Fourier-Domain OCT Karolinne Maia Rocha, M.D., Ph.D J. Bradley Randleman, M.D. R. Doyle Stulting, M.D., Ph.D. The authors have no financial interest

Purpose To assess the corneal architecture and the reproducibility of laser in situ keratomileusis (LASIK) flap thickness created by a mechanical microkeratome using a Fourier-domain optical coherence tomography (OCT).

Methods Prospective study 58 LASIK flaps (Amadeus II - Ziemer,140µm head, 9.0 and 9.5mm suction rings, ML7090CLB - Med-Logics blades) Intraoperative ultrasound (US) pachymetry flap thickness measurement Fourier-domain OCT (Optovue RTVue-100) flap morphology evaluation at 2 weeks postoperatively

Methods The flap thickness was assessed twice at : Fourier-domain OCT Analysis The flap thickness was assessed twice at : 10 points across the central 6-mm of the corneal apex (horizontal and vertical meridians) 1.5-mm from the edge of the flap superior and inferiorly

Time Domain vs Fourier Domain Visante OCT 1000 (Carl Zeiss) 2000 A scans/second depth resolution of 18 µm transverse resolution of 60 µm Scan beam wavelength: 1310 nm Exposure power at pupil 5 W The scan range is 3 mm in depth to 10 mm in transverse direction. RTVue device (Optovue) 26,000 A scans/second depth resolution of 5 µm transverse resolution of 15 µm Scan beam wavelength: 840±10 nm Exposure power at pupil 750 W Cornea–Anterior Module (CAM) additional software on the device, The CAM L lens allows 6 x 6-mm scans of the cornea

Time Domain vs Fourier Domain

OCT - Horizontal

OCT - Horizontal

Results Postoperative OCT = 111.7±11µm Intraoperative US pachymetry = 107.2±14µm Postoperative OCT = 111.7±11µm No statistically significant difference (p=0.07) The OCT measurements showed a planar flap SD across the flap = 4.9µm, SD for the 6-mm central measurements = 11µm SD range across the flap= 2 to 9µm

Conclusion The Amadeus II microkeratome with Med-Logics blades created regular, planar flaps as demonstrated by the Fourier-domain OCT. Central flap thickness measured by intraoperative US pachymetry was comparable to that measured 2 weeks postoperative by OCT.

Thank you karolinnemaia@gmail.com