Representative electron density maps

Slides:

Advertisements

Similar presentations

Individualized pain management plan.

Advertisements

Isotope‐based Fluvial Organic Carbon (ISOFLOC) Model: Model formulation, sensitivity, and evaluation Reach‐scale conceptual model of the fluvial carbon.

Isotope‐based Fluvial Organic Carbon (ISOFLOC) Model: Model formulation, sensitivity, and evaluation Modeling domain for the main stem of the South Elkhorn.

(a) illuminance measured in the horizontal plane from a typical street light (Phillips Cosmopolis, metal halide lamp). The intensity of light decays rapidly.

Isotope‐based Fluvial Organic Carbon (ISOFLOC) Model: Model formulation, sensitivity, and evaluation Sensitivity analysis of the ISOFLOC model displays.

Isotope‐based Fluvial Organic Carbon (ISOFLOC) Model: Model formulation, sensitivity, and evaluation Model flowchart for ISOFLOC which details inputs,

Evening evapotranspirative cooling in relation to vegetation and urban geometry in the city of Ouagadougou, Burkina Faso Relation between sky view factor.

Matrilin‐2 prevents the TNFα‐induced apoptosis of WB‐F344 cells via suppressing JNK pathway Matrilin‐2 knockdown promotes the apoptosis of WB‐F344 cells.

KLF4 is a key determinant in the development and progression of cerebral cavernous malformations qRT–PCR analysis of Klf4 during disease progression at.

Defective immune responses in mice lacking LUBAC‐mediated linear ubiquitination in B cells Cpdm mice show residual LUBAC‐mediated linear polyubiquitination.

Details of the binding sites of tetracycline and edeine

The mitochondrial outer membrane protein MDI promotes local protein synthesis and mtDNA replication Representative images of wt and mdi1 ovarioles stained.

Co‐immunoprecipitation of Larp with MDI‐myc in transfected S2 cells

Allelic exchange at the endogenous genomic locus in Plasmodium falciparum proves the role of dihydropteroate synthase in sulfadoxine‐resistant malaria.

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries Global Maps Presenting the Most.

Exogenous N‐acyl‐homoserine lactones enhance the expression of flagella of Pseudomonas syringae and activate defence responses in plants Comparisons of.

Binding of p38α and p38β2 to MAP kinase kinases

The trimeric coiled‐coil HSBP1 protein promotes WASH complex assembly at centrosomes MDA‐MB‐231 cells expressing HaloTag WASH or CCDC53 were stained with.

Regional weather and climates of the British Isles ‐ Part 1: Introduction The annual rainfall anomaly (percentage difference from normal) for Western Scotland.

Projected changes in prevailing winds for transatlantic migratory birds under global warming Meridional (first row) and zonal wind speed anomalies (second.

Model for interaction with promoter DNA and nascent RNA

Sequence alignments of phage‐type RNA polymerases and lysozymes

Applications of genome‐scale metabolic reconstructions

Endosome and Golgi‐associated degradation (EGAD) of membrane proteins regulates sphingolipid metabolism Equal amounts of WT cells and indicated single.

Retinoids activate proton transport by the uncoupling proteins UCP1 and UCP2 (A) pH dependency of the state 4 respiratory rate: control ▵ and UCP2 mitochondria.

Anthropogenic noise weakens territorial response to intruder's songs

Potent enzyme inhibitors derived from dromedary heavy‐chain antibodies

Retinoids activate proton transport by the uncoupling proteins UCP1 and UCP2 (A) Effect of palmitic acid on the respiratory rate of mitochondria isolated.

Prevalence of women with advanced maternal age by country.

Model for end‐stage liver disease exception points for treatment‐responsive hepatocellular carcinoma Treatment‐responsive HCC: patient with complete response.

Taurine as a constituent of mitochondrial tRNAs: new insights into the functions of taurine and human mitochondrial diseases Schematic depiction of modification.

Sequential treatment with 5‐aza‐2′‐deoxycytidine and deacetylase inhibitors reactivates HIV‐1 One night after cell purification, CD8+‐depleted PBMCs from.

Sequential treatment with 5‐aza‐2′‐deoxycytidine and deacetylase inhibitors reactivates HIV‐1 One night after cell purification, HLA DR− CD69− CD25− CD4+

Induced chromosome deletions cause hypersociability and other features of Williams–Beuren syndrome in mice Expression of genes measured by real‐time qRT‐PCR.

Cyclin D2 protein is expressed in the developing human cortex

Schematic presentation of the peptide array

Structural and functional analysis of the GABARAP interaction motif (GIM) Interaction profile of 30 biotinylated LIR peptides from various proteins against.

DAP‐kinase is a Ca2+/calmodulin‐dependent, cytoskeletal‐associated protein kinase, with cell death‐inducing functions that depend on its catalytic activity.

Parallel versus antiparallel arrangement of NSF‐D1 and NSF‐D2

Absolute quantification of translational regulation and burden using combined sequencing approaches Genetic design of the LacZ reporter construct whose.

Mammary stem cells and progenitors: targeting the roots of breast cancer for prevention (A) Schematic of the human breast highlighting terminal ductal.

Establishment of the pancreas organoids from adult pancreatic ducts

Unlimited in vitro expansion of adult bi‐potent pancreas progenitors through the Lgr5/R‐spondin axis Clonal expansion of single Lgr5 cells derived from.

Mapping the interaction of Snf1 with TORC1 in Saccharomyces cerevisiae

Involvement of Crm1 in the hemin‐induced nuclear exclusion of Bach1

Kinesin‐2 motors adapt their stepping behavior for processive transport on axonemes and microtubules A–CThe movement of single KLP3A/B motors fluorescently.

Annexin A1 attenuates EMT and metastatic potential in breast cancer

Extensive quantitative remodeling of the proteome between normal colon tissue and adenocarcinoma Abundance of proteins matching selected subcellular locations.

HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC‐to‐EpiSC/hESC transition Expression of nuclear‐encoded mitochondrial.

Heterogeneity in Δψmit reported by TMRE

Mitochondria are morphologically and functionally heterogeneous within cells Surface‐rendered three‐dimensional reconstructions of cells expressing mito‐DsRed1.

Dual melanocortin‐4 receptor and GLP‐1 receptor agonism amplifies metabolic benefits in diet‐induced obese mice A–DCholesterol metabolic parameters were.

Asynchronous PTP activation within a single cell

Update of the Scientific Opinion on the risks to plant health posed by Xylella fastidiosa in the EU territory Boxplots for how (a) landscape type, (b)

Cesarean section scar diverticulum evaluation by saline contrast‐enhanced magnetic resonance imaging: The relationship between variable parameters and.

The p97/VCP ATPase is critical in muscle atrophy and the accelerated degradation of muscle proteins The content of p97 and two of its cofactors are induced.

The p97/VCP ATPase is critical in muscle atrophy and the accelerated degradation of muscle proteins Electroporation of DNp97 in TA blocks both denervation.

Schematic diagram of MAPKKK5 constructs

The Arabidopsis CERK1‐associated kinase PBL27 connects chitin perception to MAPK activation The neighbor‐joining phylogenetic tree was created using ClustalW.

M‐LDH serves as a sarcolemmal KATP channel subunit essential for cell protection against ischemia The opening of KATP channels and intact activity of M‐LDH.

STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells IL‐3‐induced apoptosis in Ba/F3 cells expressing.

Processive movement of single kinesins on crowded microtubules visualized using quantum dots Effect of the mutant E164A on the motility of single quantum.

The Escherichia coli RNA polymerase α subunit linker: length requirements for transcription activation at CRP‐dependent promoters Comparison of the effect.

EglN2 associates with the NRF1‐PGC1α complex and controls mitochondrial function in breast cancer A, BqRT–PCR of mRNA from T47D transfected with either.

Imaging Disaster: Puerto Rico through the Eye of Hurricane María

CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression Immunoprecipitation of CD147 from RBL.

CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression The transmembrane and cytoplasmic regions.

The heterotetrameric architecture of the epithelial sodium channel (ENaC) ENaC expressed at the cell surface is composed of a fixed number of α, β and.

Notch inhibits apoptosis by direct interference with XIAP ubiquitination and degradation Interaction between XIAP and the endogenously generated Notch.

Range expansion and distributional limits of the nine‐banded armadillo in the United States: an update of Taulman & Robbins () Estimated boundary of the.

Presentation transcript:

Structure of T7 RNA polymerase complexed to the transcriptional inhibitor T7 lysozyme Representative electron density maps. (A) Residues 734–739 of an intermediate model of the PL complex are superimposed onto the final 4‐fold domain averaged electron density map (20–3.0 Å) in crystal form III. The map is contoured at 1.3σ. (B) An annealed 2Fo−Fc omit electron density map, calculated by excluding residues 734–739 of the final PL complex model. The map is contoured at 1.3σ. IF THIS IMAGE HAS BEEN PROVIDED BY OR IS OWNED BY A THIRD PARTY, AS INDICATED IN THE CAPTION LINE, THEN FURTHER PERMISSION MAY BE NEEDED BEFORE ANY FURTHER USE. PLEASE CONTACT WILEY'S PERMISSIONS DEPARTMENT ON PERMISSIONS@WILEY.COM OR USE THE RIGHTSLINK SERVICE BY CLICKING ON THE 'REQUEST PERMISSIONS' LINK ACCOMPANYING THIS ARTICLE. WILEY OR AUTHOR OWNED IMAGES MAY BE USED FOR NON-COMMERCIAL PURPOSES, SUBJECT TO PROPER CITATION OF THE ARTICLE, AUTHOR, AND PUBLISHER. EMBO J, Volume: 17, Issue: 14, Pages: 4101-4113, First published: 15 July 1998, DOI: (10.1093/emboj/17.14.4101)