Pituitary Gland Thyrotoxicosis Adrenal Gland Thyroid/Parathyroid Bone Health Skin + Heart $100 $100 $100 $100 $100 $200 $200 $200 $200 $200 $300 $300 $300 $300 $300 $400 $400 $400 $400 $400 $500 $500 $500 $500 $500

What are bilateral adrenal pheochromocytomas?

Pheochromocytoma Rule of 10’s 10% Found incidentally 10% Familial (MEN2A, MEN2B) 10% Extra-adrenal 10% Bilateral (multiple) 10% Calcify 10% Children 10% Recurrence 10% Malignant

Multiple Endocrine Neoplasia2 (MEN2) MEN2A Medullary thyroid cancer Pheochromocytoma Parathyroid adenoma MEN2B Mucosal neuromas (lips and tongue) Marfanoid habitus

Pheochromocytoma Rare but fatal catecholamines producing tumor Incidence: 2-8/million people/year Account for 4% of adrenal incidentaloma Rule of 10’s: 10% bilateral, 10% extra-adrenal, 10% familial, 10% malignant Aside from catecholamines, it can also secrete dopamine, ACTH, PTH, calcitonin, vaso-intestinal polypeptide

Blake MA, Kalra MK, Maher MM, et al Blake MA, Kalra MK, Maher MM, et al. Pheochromocytoma: An imaging chameleon. Radiographics. 2004;24:S87–S99.

Pheochromocytoma Rare but fatal catecholamines producing tumor Incidence: 2-8/million people/year Account for 4% of adrenal incidentaloma Rule of 10’s: 10% bilateral, 10% extra-adrenal, 10% familial, 10% malignant Aside from catecholamines, it can also secrete dopamine, ACTH, PTH, calcitonin, vaso-intestinal polypeptide

Blake MA, Kalra MK, Maher MM, et al Blake MA, Kalra MK, Maher MM, et al. Pheochromocytoma: An imaging chameleon. Radiographics. 2004;24:S87–S99.