Low-grade dysplasia in Barrett’s esophagus

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Low-grade dysplasia in Barrett’s esophagus Prateek Sharma Gastroenterology Volume 127, Issue 4, Pages 1233-1238 (October 2004) DOI: 10.1053/j.gastro.2004.07.061 Copyright © 2004 American Gastroenterological Association Terms and Conditions

Figure 1 Areas of low-grade dysplasia (LGD) (green arrow) in a biopsy specimen of a patient with Barrett’s esophagus. The nuclei are hyperchromatic, have irregular nuclear contours and are overlapping. This is in contrast to areas without dysplasia (blue arrow). Courtesy of John Goldblum, M.D., Cleveland Clinic, Cleveland, Ohio. Gastroenterology 2004 127, 1233-1238DOI: (10.1053/j.gastro.2004.07.061) Copyright © 2004 American Gastroenterological Association Terms and Conditions

Figure 2 Photomicrograph of a biopsy specimen harboring low-grade dysplasia (LGD), including surface epithelium showing cytological atypia (arrow). Courtesy of John Goldblum, M.D., Cleveland Clinic, Cleveland, Ohio. Gastroenterology 2004 127, 1233-1238DOI: (10.1053/j.gastro.2004.07.061) Copyright © 2004 American Gastroenterological Association Terms and Conditions

Figure 3 Outcome of low-grade dysplasia (LGD) in a large Barrett’s database. The majority of the patients fail to have LGD detected during follow-up. Gastroenterology 2004 127, 1233-1238DOI: (10.1053/j.gastro.2004.07.061) Copyright © 2004 American Gastroenterological Association Terms and Conditions