Zhijian Wu, Aravind Asokan, R. Jude Samulski Molecular Therapy

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Adeno-associated Virus Serotypes: Vector Toolkit for Human Gene Therapy Zhijian Wu, Aravind Asokan, R. Jude Samulski Molecular Therapy Volume 14, Issue 3, Pages 316-327 (September 2006) DOI: 10.1016/j.ymthe.2006.05.009 Copyright © 2006 The American Society of Gene Therapy Terms and Conditions

FIG. 1 Illustrative example of the hierarchy of transduction of AAV serotypes 1–5 cross-packaged with AAV type 2 vector genomes in different tissues. (A) GFP expression in the retina of Wistar rats after 1 month subsequent to subretinal injection with AAV serotypes 1 through 5. (B) Luciferase expression in skeletal muscle of Balb/C mice 2 months following intramuscular injection of AAV serotypes 1 through 5. Molecular Therapy 2006 14, 316-327DOI: (10.1016/j.ymthe.2006.05.009) Copyright © 2006 The American Society of Gene Therapy Terms and Conditions