Fig. 2 Hydrogel stress relaxation regulates cell cycle progression from the G1 phase to the S phase. Hydrogel stress relaxation regulates cell cycle progression.

Slides:

Advertisements

Similar presentations

Fig. 3 Cytosolic delivery of fluorescent proteins.

Advertisements

Fig. 3 The electrical contact of direct-printed and reconfigured liquid metals. The electrical contact of direct-printed and reconfigured liquid metals.

Fig. 2 Global production, use, and fate of polymer resins, synthetic fibers, and additives (1950 to 2015; in million metric tons). Global production, use,

Fig. 4 INS spectra of different human bones from the Roman period [humerus, ulna, femur, and fibula from the same skeleton, Guidonia-Montecelio, Italy.

Fig. 2 CFD results. CFD results. Results of CFD simulations in horizontal (left column) and vertical (right column) cross-sections. All models oriented.

Fig. 3 Vibrational spectra of human bones from the Copper Age (Scoglietto cave, Italy). Vibrational spectra of human bones from the Copper Age (Scoglietto.

Vibrational spectra of medieval human bones (Leopoli-Cencelle, Italy)

Fig. 5 Thermal conductivity of n-type ZrCoBi-based half-Heuslers.

Fig. 1 Map of water stress and shale plays.

Fig. 1 Crystal and electronic structure of WTe2.

Fig. 3 Electron PSD in various regions.

Fig. 4 Complete separation of water and solute after stable and efficient solar evaporation. Complete separation of water and solute after stable and efficient.

Fig. 4 Resynthesized complex boronic acid derivatives based on different scaffolds on a millimole scale and corresponding yields. Resynthesized complex.

HT synthesis of boronic acids using the building block approach

Fig. 6 Comparison of properties of water models.

Fig. 1 Mean and median RCR (Relative Citation Ratio) of Roadmap Epigenomics Program research articles for each year. Mean and median RCR (Relative Citation.

Fig. 2 Influence of the Roadmap Epigenomics Program on the field of epigenomics research. Influence of the Roadmap Epigenomics Program on the field of.

Fig. 2 Ferroelectric domains resolved in WTe2 single crystals.

Fig. 3 Glucose- and structure-dependent insulin release.

Fig. 2 TRXSS data. TRXSS data. TRXSS data covering delay times from 10 ns to 10 ms for wild-type DmCry (A), for the DmCry(H378A) mutant (B), and for XlPho.

Fig. 2 Stratigraphic profile of the Area 15 excavation block showing the diagnostic cultural materials and components alongside the stratigraphic sequence.

Fig. 3 Rotation experiment, setup.

Fig. 1 Product lifetime distributions for the eight industrial use sectors plotted as log-normal probability distribution functions (PDF). Product lifetime.

Fig. 5 Structural photocycle for DmCry.

FTIR-ATR spectra of Neolithic faunal bones (Mora Cavorso cave, Italy)

Fig. 3 Gate voltage dependence of the areal iDMI and PMA.

Fig. 3 Phase-contrast imaging.

Fig. 1 Schematic illustration of the preparation and potential application of FMSMs. Schematic illustration of the preparation and potential application.

Fig. 1 Bioinspired design of AAD for promoting wound contraction.

Fig. 1 Distribution of total and fake news shares.

Fig. 2 2D QWs of different propagation lengths.

Fig. 1 Map of the study area including the northwestern end of the Hawaiian Ridge and the southern portion of the ESC. Map of the study area including.

Fig. 1 Structure of L10-IrMn.

Fig. 4 EUV TG signal from Si.

Fig. 3 ET dynamics on the control and treatment watersheds during the pretreatment and treatment periods. ET dynamics on the control and treatment watersheds.

Fig. 1 Histograms of the number of first messages received by men and women in each of our four cities. Histograms of the number of first messages received.

Fig. 5 Schematic phase diagrams of Ising spin systems and Mott transition systems. Schematic phase diagrams of Ising spin systems and Mott transition systems.

Fig. 1 Average contribution (million metric tons) of seafood-producing sectors, 2009–2014. Average contribution (million metric tons) of seafood-producing.

Fig. 4 The mechanical performances of thermally stable click-ionogels.

Fig. 4 Praying Prophet by Lorenzo Monaco: Mapping lake pigments and associated substrate. Praying Prophet by Lorenzo Monaco: Mapping lake pigments and.

Fig. 4 Evolution of fraction of sickled RBCs under hypoxia.

Fig. 2 Magnetic properties of FGT/Pt bilayer.

Fig. 3 Production of protein and Fe(II) at the end of growth correlated with increasing concentrations of ferrihydrite in the media that contained 0.2.

Fig. 2 Schematic drawings of Göbekli Tepe skulls.

Fig. 4 Relationships between light and economic parameters.

Fig. 5 Comparison of the liquid products generated from photocatalytic CO2 reduction reactions (CO2RR) and CO reduction reactions (CORR) on two catalysts.

Schematic of the proposed brain-controlled assistive hearing device

Fig. 5 Skull 1: Tentative reconstruction.

Fig. 1 Location of the Jirzankal Cemetery.

Fig. 6 MSC encapsulation in vitro within PdBT cross-linked gels.

Fig. 1 Structural and electrical properties of Bi2Se3/BaFe12O19.

Multiplexed four- and eight-channel devices for rapid processing

Fig. 2 Mean field results. Mean field results. (A) Solutions P(x) to Eq. 4 for a range of T and wc = (B) Modulus ∣pk∣ of order parameters versus.

Fig. 3 Comparisons of NDVI trends over the globally vegetated areas from 1982 to Comparisons of NDVI trends over the globally vegetated areas from.

Fig. 3 Electronic conductivity studies.

Fig. 1 Schematic depiction of a paradigm for rapid and guided discovery of materials through iterative combination of ML with HiTp experimentation. Schematic.

Fig. 2 In situ extraction of miRNAs using the nanowire-anchored microfluidic device. In situ extraction of miRNAs using the nanowire-anchored microfluidic.

Fig. 4 Spatial mapping of the distribution and intensity of industrial fishing catch. Spatial mapping of the distribution and intensity of industrial fishing.

Fig. 4 Single-particle contact angle measurements.

Fig. 3 Performance of the generative model G, with and without stack-augmented memory. Performance of the generative model G, with and without stack-augmented.

Fig. 4 Behavior of resistance peak near density nm = 5.

Fig. 2 Comparison between the different reflective metasurface proposals when θi = 0° and θr = 70°. Comparison between the different reflective metasurface.

Fig. 3 Characterization of the luminescence temporal time traces.

Fig. 3 Supercurrents in various conductance plateau regions.

Fig. 1 Doping schematics and optical properties.

Fig. 4 Effects of individual picosecond and microsecond pulses.

Fig. 3 Calculated electronic structure of ZrCoBi.

Fig. 3 Photothermal property and disassembly behavior study of the self-assembled nanostructures. Photothermal property and disassembly behavior study.

Fig. 5 CD19-tPSMA(N9del) CAR T cell numbers in mouse and human.

Fig. 3 Temperature-dependent heat capacity of YbTM2Zn20.

Presentation transcript:

Fig. 2 Hydrogel stress relaxation regulates cell cycle progression from the G1 phase to the S phase. Hydrogel stress relaxation regulates cell cycle progression from the G1 phase to the S phase. (A) Cell cycle analysis of cells cultured in slow-, medium-, and fast-relaxing gels for 10 days, measured by flow cytometry. Inset, fluorescence intensity (FI) versus forward scatter (FSC). Red rectangle indicates a gate of cell population. A.U., arbitrary units. (B) Population of cells in G0/G1, S, and G2/M phases in soft (3 kPa) and stiff (16 kPa) gels with varying relaxation (n = 2 to 4 per each condition). (C) Population of cells in the G0/G1 phase as a function of relaxation time. (D) A schematic of cell cycle progression including a mechanical checkpoint associated with hydrogel relaxation or mechanical confinement identified by the studies. Data are shown as means ± SD. Sungmin Nam et al. Sci Adv 2019;5:eaaw6171 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).