Immune/inflammatory infiltrates in colorectal cancer tissue.

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Immune/inflammatory infiltrates in colorectal cancer tissue. Immune/inflammatory infiltrates in colorectal cancer tissue. Left panel: The T cell infiltrate also co-localizes with mature DCs (as shown by CD83 immunostaining). The number of DCs is not so abundant compared with that in secondary lymphoid tissue. Right panel: CD68+ macrophages abundantly distributed along the invasive margin also express B7-2 (CD86) and HLA-DR (not shown), a phenotype similar to that of mature DCs. Haruo Ohtani Cancer Immun 2007;7:4 Copyright © 2007 by Haruo Ohtani