The repertoire of NPC-derived cells within the CC during cuprizone-induced demyelination. The repertoire of NPC-derived cells within the CC during cuprizone-induced.

Slides:

Advertisements

Similar presentations

Volume 3, Issue 4, Pages (October 2014)

Advertisements

Identification of combination treatment–responsive dysfunctional tumor-infiltrating CD8+ T cell population. Identification of combination treatment–responsive.

Volume 17, Issue 5, Pages (November 2015)

AG-221 induces the differentiation of IDH2R140Q blasts along myeloid lineages in primary human AML xenograft models. AG-221 induces the differentiation.

Fig. 1. BCAS1 expression identifies newly generated oligodendrocytes.

Density of dendritic spines on L2/3 pyramidal neurons is greater in visual cortex of germline PirB−/− mice than in PirB+/+ mice at P30. Density of dendritic.

Volume 22, Issue 1, Pages 8-16 (January 2018)

Promoting Myelin Repair through In Vivo Neuroblast Reprogramming

Volume 3, Issue 4, Pages (October 2014)

MAPKKK5-induced cell death is independent of Ser-289 phosphorylation.

FGF-2 signaling mediates expansion of HSPCs

Active avoidance is impaired in aged mice in both multimodal and visual versions of the task. Active avoidance is impaired in aged mice in both multimodal.

TANs mediate obesity-induced tumor progression and aggravated desmoplasia. TANs mediate obesity-induced tumor progression and aggravated desmoplasia. A,

Whole-cell patch-clamp analysis of NAc cells.

Volume 9, Issue 6, Pages (December 2017)

Fig. 2. Proportion of motile objects and track length

The mucosal environment regulates CD160 expression on IELs

Fig. 5. Onecut transcription factors are important for the correct generation of the mdDA neuronal population.(A) Schematic representation of the region.

Effect of 14 hit compounds on SMN protein expression in type I SMA patient fibroblast cells (GM03813). Effect of 14 hit compounds on SMN protein expression.

OTX2 transfers into supporting cells of neurogenic niches.

The complexity as well as the total dendritic length of ApoE-deficient adult-born granule cells are significantly reduced. The complexity as well as the.

The complexity and the total dendritic length of ApoE4 adult-born granule cells are significantly reduced. The complexity and the total dendritic length.

APT1 palmitoylation and localization.

Effect of FGF8 on R-C marker expression.

Increased phosphorylation of Akt, Girdin S1416, and NR2B of NMDA receptor in the hippocampus of mouse after fear conditioning. Increased phosphorylation.

Diclofenac treatment reduces L-selectin on peripheral blood and infiltrated leukocytes but does not alter accumulation in the injured spinal cord. Diclofenac.

Loss of Nrf2 function in vivo increased cortical damage after permanent focal ischemia. Loss of Nrf2 function in vivo increased cortical damage after permanent.

Deletion of HtrA1 does not alter vascular or immune cell morphology or distribution in the young-adult mouse neocortex. Deletion of HtrA1 does not alter.

Microglia activation in distinct sites of the spinal cord from mice with bronchial asthma or atopic dermatitis on the back skin at the thoracic spinal.

Temporal origins of h-ChCs labeled in Cdh6-CreER;Dlx5/6-Flp;Ai65 mice.

Aβ-mediated Ras-MAPK signaling and Cyclin D1 expression in B103 cells are dependent on APP expression and can be reversed with MEK or Ras inhibition. Aβ-mediated.

Volume 11, Issue 6, Pages (December 2018)

Interference of Kv4 in dorsal neurons (DN1s) does not significantly regulate sleep onset. Interference of Kv4 in dorsal neurons (DN1s) does not significantly.

Distribution of examined mRNAs across CeA subcompartments.

Gene delivery of ChABC leads to reduced neuronal death associated with lower levels of apoptosis at 1 week postinjury. Gene delivery of ChABC leads to.

ADCY5 is expressed in isolated human islets and affected by T2D risk alleles. ADCY5 is expressed in isolated human islets and affected by T2D risk alleles.

PTZ-induced neuronal activity visualized by IEGs

Volume 9, Issue 3, Pages (September 2017)

NRG1 activates cortical erbB4 receptors and increases excitation onto PV+ interneurons. NRG1 activates cortical erbB4 receptors and increases excitation.

Transgenic expression of mCREB or CREB produces opposite effects in the learned helplessness model of depression. Transgenic expression of mCREB or CREB.

Sox11 and Sox4 are dynamically expressed during corticogenesis in overlapping and discrete cellular populations. Sox11 and Sox4 are dynamically expressed.

Peripheral surgery regulates expression of astrocytic markers.

The developmental spine morphology changes predict decreased biochemical compartmentalization with age, while loss of FMRP subtly influences this in an.

Fig. 4 Reconstitution of MCs in KitW-sh/W-sh mice increases IL-10+ Breg cells and suppresses the CHS response. Reconstitution of MCs in KitW-sh/W-sh mice.

Referred visceral hyperalgesia in wild-type (+/+) and Nav1

Quantitative analysis of effects of the Egr inhibitor construct on neurite outgrowth. Quantitative analysis of effects of the Egr inhibitor construct on.

A, Cells present in clonal clusters were classified based on morphology (see Materials and Methods) into type 1 progenitor cells (A.1); type 2/3 progenitor.

Minocycline treatment inhibited dorsal column transection-induced glial cell death within the distal and proximal AST. A, Percentage of apoptotic microglia/macrophages.

Distribution of NE- and KCl-responsive precursor cells along the septotemporal axis of the hippocampus. Distribution of NE- and KCl-responsive precursor.

GABA and corticosterone selectively affect the activity of NE- and KCl-responsive precursor cells. GABA and corticosterone selectively affect the activity.

NPC-derived oligodendrocytes are maintained long term after cuprizone challenge. NPC-derived oligodendrocytes are maintained long term after cuprizone.

CT-26 colon cancer induces the recruitment of protumor mast cells and the accumulation of MDSCs. CT-26 colon carcinoma cells (2 × 105) were injected s.c.

FMRP S499 rephosphorylation kinetics after CX-4945 treatment and washout mirrors a known CK2 target. FMRP S499 rephosphorylation kinetics after CX-4945.

The dopamine (DA) response to cocaine infusion in the NAc in constitutive p11 KO mice is restored by nicotinic or muscarinic receptor stimulation in the.

Conversion of CD11bhighCD27high NK cells into MDSCs leads to CD11bhighCD27high and CD11bhighCD27low NK cell reduction. Conversion of CD11bhighCD27high.

A, Hippocampal protein levels of IL-6 in LD and DD mice treated with PDTC, ASA, or saline controls. A, Hippocampal protein levels of IL-6 in LD and DD.

Nerve injury induces mechanical hypersensitivity.

Fig. 2 Phenotypic analyses of Bcl11b-deficient Treg cells.

Absence of PC-induced ischemic tolerance in P2X7−/− mice.

Coexpression of Crf and Tac2 (A-P -1.5).

FKBP1b counters the age-related decrease in hippocampal MAP2 protein expression. FKBP1b counters the age-related decrease in hippocampal MAP2 protein expression.

Irradiated whole-cell vaccination with MOC1, but not MOC2, induces immunologic memory. Irradiated whole-cell vaccination with MOC1, but not MOC2, induces.

Leptin-mediated electrophysiological activation of POMC neurons.

Quantification of TUNEL staining and OS length among the rab11a constructs. Quantification of TUNEL staining and OS length among the rab11a constructs.

Knockdown of NR2A and NR2B leads to distinct rearrangements of the dendritic arbor architecture. Knockdown of NR2A and NR2B leads to distinct rearrangements.

Passive immunization with CT α-syn antibodies improved TH pathology and neuroinflammation in the striatum of α-syn tg mice. Passive immunization with CT.

ΔFosB regulates spike number in hippocampal CA1 neurons.

NEDD9 binding to AURKA decreases the efficacy of AURKA inhibitors in vitro. NEDD9 binding to AURKA decreases the efficacy of AURKA inhibitors in vitro.

The effect of βAR signaling on the generation of a cytotoxic CD8+ T-cell response in vivo. The effect of βAR signaling on the generation of a cytotoxic.

Partial restoration of impaired LTP in hippocampal slices from 12-month-old NCAM−/− mice through inhibition of GluN2B-containing receptor signaling. Partial.

Presentation transcript:

The repertoire of NPC-derived cells within the CC during cuprizone-induced demyelination. The repertoire of NPC-derived cells within the CC during cuprizone-induced demyelination. A, Mediolateral distributions of the total population of YFP+ NPC-derived cells in the rostral, middle, and caudal CC of TAM/cuprizone-challenged Nestin:YFP mice at 2, 3, and 4 weeks of cuprizone challenge. B, Quantification of total YFP+ NPC-derived cells in the CC adjacent to the SVZ revealed a significant recruitment of cells in the rostral and caudal CC starting at 2 weeks of cuprizone challenge, with no significant increase being observed in the middle CC. Two-way ANOVA was used to compare the mean density of YFP+ cells among 2, 3, and 4 weeks of cuprizone challenge for each segment of the CC (**p < 0.01, ****p < 0.0001). C, Percentage of YFP+ cells expressing Sox10, GFAP, and/or Dcx in the rostral, middle, and caudal CC of TAM/cuprizone Nestin:YFP mice examined after 4 weeks of cuprizone challenge. D, Plot of the percentage of YFP+ NPC-derived cells that express CC1 or PDGFRα after 4 weeks of cuprizone challenge. Mean ± SEM values are shown. Yao Lulu Xing et al. J. Neurosci. 2014;34:14128-14146 ©2014 by Society for Neuroscience