Codon Wheel/tRNA passer mRNA mover In a group of 4, you are also the Recorder Determine the codon, anticodon, and amino acid for the first codon in the P site. Tell the tRNA maker and the Recorder. For each subsequent codon, pass the codon wheel in this order: Recorder, tRNA maker, mRNA mover, Protein Builder Pass each anticodon loop from the tRNA maker to the Protein builder mRNA mover Move the mRNA strand across the ribosome at the appropriate times Announce the colors, in order, of the K’nex pieces in the P site at step 1. At subsequent steps, announce the colors in the A site. Determine the codon, anticodon, and amino acid when the codon wheel comes to you. Tell the tRNA maker and the Recorder. Protein builder Receive anticodon loops from the tRNA passer Place the anticodon loop at the P or A site so that the anticodon letters match up with the K’nex pieces. Verify that these form correct base pairs (A-U or G-C). When the second codon moves to the P site, attach the first and second amino acids and remove the first anticodon loop from the model. Repeat for each subsequent movement of the mRNA across the ribosome Determine the codon, anticodon, and amino acid when the codon wheel comes to you. Tell the tRNA maker and the Recorder Recorder Make sure that you have the worksheet Record each students’ name Cut strips of tape for the tRNA maker At each step, record the codon, anticodon, and amino acid announced Determine the codon, anticodon, and amino acid when the codon wheel comes to you. Tell the tRNA maker and record what you determined. tRNA maker Cut slits on opposite sides of paper strips on the solid marks Record announced anticodon in the blocks on a paper strip Fold the strip into a tRNA anticodon loop and secure by interlocking slits Choose a pop bead to represent the announced amino acid, and attach it to the loop with tape Pass the anticodon loop to the tRNA passer to give to the Protein builder Determine the codon, anticodon, and amino acid when the codon wheel comes to you. Tell the tRNA maker and the Recorder.