Fig. 3 A hypothetical application of the conceptual model using a case study for which antidepressant prescription is the outcome. A hypothetical application.

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Fig. 3 A hypothetical application of the conceptual model using a case study for which antidepressant prescription is the outcome. A hypothetical application of the conceptual model using a case study for which antidepressant prescription is the outcome. Information is gathered for each of the three steps. (1) Natural features in this case are street trees (other characteristics unspecified, including spatial configuration). (2) Exposure is calculated using a cumulative exposure approach regarding residential street tree density (spatial configuration illustrated here for conceptual purposes but not relevant to this estimation metric). (3) Dose and/or interaction were not taken into account. (4) The effect of decreased antidepressant (AD) prescriptions in areas with more street trees is represented along with other potential benefits (e.g., stress and working memory) not projected specifically in this case, although they are represented conceptually. As illustrated in Fig. 1, different nature options provide benefits that we can quantify over and above a “no nature” version of an urban plan. The model allows us to compare net benefits (total benefits less costs) of different viable plans. Benefits will also likely vary according to the moderating influences of individual differences and sociocultural context, here represented conceptually by groups A to D, as people receive different benefits from nature experience given these moderators. Photographs are from the public domain and free for public use. Gregory N. Bratman et al. Sci Adv 2019;5:eaax0903 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).