Quantification of conjunctival vascular reaction by digital imaging

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Presentation transcript:

Quantification of conjunctival vascular reaction by digital imaging Friedrich Horak, MDa, Uwe Bergera, Reinhard Menapace, MDb, Norbert Schuster, PDc Journal of Allergy and Clinical Immunology Volume 98, Issue 3, Pages 495-500 (September 1996) DOI: 10.1016/S0091-6749(96)70081-7 Copyright © 1996 Mosby, Inc. Terms and Conditions

FIG. 1 Vascular reaction of the conjunctiva (area of 2.5 × 3.3 mm) after a CPT. Consecutive digital imaging of the vascular reaction every 3 minutes. Linear increase of red density in conjunctiva until 15 minutes after challenge is demonstrated. Journal of Allergy and Clinical Immunology 1996 98, 495-500DOI: (10.1016/S0091-6749(96)70081-7) Copyright © 1996 Mosby, Inc. Terms and Conditions

FIG. 2 Objective red density of conjunctiva (mean red density of digital image analysis of left eye) during a long-term challenge with grass pollen grains. Patients were given active (azelastine) or placebo treatment 1 hour before the challenge session. Statistical results are listed in Table I. Journal of Allergy and Clinical Immunology 1996 98, 495-500DOI: (10.1016/S0091-6749(96)70081-7) Copyright © 1996 Mosby, Inc. Terms and Conditions

FIG. 3 Subjective scoring of itching eye (mean of a 100 mm visual analog score) during a long-term challenge with grass pollen grains. Patients were given active (azelastine) or placebo treatment 1 hour before the challenge session. Subjective parameters are consistent with the objective data (Fig. 2); however, differences are not so clear. VAS, Visual analog scale. Journal of Allergy and Clinical Immunology 1996 98, 495-500DOI: (10.1016/S0091-6749(96)70081-7) Copyright © 1996 Mosby, Inc. Terms and Conditions