Fig. 4. Effects of natriuretic peptide receptor 2 (NPR2) knockdown on cells apoptosis in mouse Leydig cells. (A) Relative mRNA expression of cell apoptosis.

Slides:

Advertisements

Similar presentations

Inhibition of PDCD6 Induces Cell Proliferation and Reduces Apoptosis in Human Epithelial Ovarian Cancer Cells Yan Huang, Xiaohua Wu Department of Gynecology,

Advertisements

Negative regulation of cell cycle by intracellular signals Checkpoint p53 detects DNA damage & activates p21 p21 inhibits cdk2-cyclinA Intracellular Regulation.

Novel agents targeting the apoptosis pathway Aaron D. Schimmer MD, PhD, FRCPC Princess Margaret Hospital Toronto, Canada.

Cell Physiol Biochem 2017;42:2582– DOI: /

Cell Physiol Biochem 2014;33: DOI: /

Selective inhibition of BCL10-induced NF-κB activation by Tat–Peptide VIII HEK-293 cells were transiently co-transfected with an expression vector encoding.

Cell Physiol Biochem 2013;32: DOI: /

From: Short Pulse of Clinical Concentration of Bevacizumab Modulates Human Retinal Pigment Epithelial Functionality Invest. Ophthalmol. Vis. Sci ;57(3):

Fig. 5. The measurement of phosphorylation of p53 level in N2A cells under high glucose condition and agmatine treatment. (A, B) p53 phosphorylation levels.

Fig. 5. Levels of apoptosis-associated proteins following treatment with parthenolide (PT) and balsalazide. HCT116 cell lysates were prepared after treatment.

WNT5A is a Key Regulator of the Epithelial-Mesenchymal Transition and Cancer Stem Cell Properties in Human Gastric Carcinoma Cells Pathobiology 2013;80:

MicroRNA-101 Inhibits Growth, Proliferation and Migration and Induces Apoptosis of Breast Cancer Cells by Targeting Sex-Determining Region Y-Box 2 Cell.

Fig. 8. Changes of caspase-3 (A), Bcl-2 (B), IL-6 (C), TNF-α (D), VEGF (E) and BNP (F) protein expression levels after hUCB-MSCs injection in PAH rat heart.

Elevated Apoptosis in the Liver of Dairy Cows with Ketosis

Elevated FOXC2 Expression Promotes Invasion of HCC Cell Lines and is Associated with Poor Prognosis in Hepatocellular Carcinoma Cell Physiol Biochem 2017;44:99–109.

Fig S1 Mannitol pre-treatment dosen’t affect RANKL-induced macrophage activation. A B To study the effect of mannitol pre-treatment, as a control for osmotic.

Concept 4: Analyzing Cell Communication

Chapter 08 The T Cell Receptor: Proteins and Genes

Cell Surface CD74–MIF Interactions Drive Melanoma Survival in Response to Interferon-γ Keiji Tanese, Yuuri Hashimoto, Zuzana Berkova, Yuling Wang, Felipe.

A Signal Transduction Pathway from TGF-β1 to SKP2 via Akt1 and c-Myc and its Correlation with Progression in Human Melanoma Xuan Qu, Liangliang Shen,

Expression of phosphorylated BNP, HIF-2 alpha and beta actin proteins in the primary tumour tissues using western blotting. Expression of phosphorylated.

Yongping Shao, Kaitlyn Le, Hanyin Cheng, Andrew E. Aplin

Droxinostat, a Histone Deacetylase Inhibitor, Induces Apoptosis in Hepatocellular Carcinoma Cell Lines via Activation of the Mitochondrial Pathway and.

The Chemopreventive Effect of Tanacetum Polycephalum Against LA7-Induced Breast Cancer in Rats and the Apoptotic Effect of a Cytotoxic Sesquiterpene.

by Daniel Sasca, Patricia S

DHEA(S) and Allo induced the expression of the antiapoptotic Bcl-2 proteins in serum-deprived PC12 cells. DHEA(S) and Allo induced the expression of the.

Dual Role of Apoptosis-Associated Speck-Like Protein Containing a CARD (ASC) in Tumorigenesis of Human Melanoma Weimin Liu, Yuchun Luo, Jeffrey H. Dunn,

Fas NF-κB JNK Bcl-2 Akt p21 Bax Ras TRAILR p53 EGFR TRADD Myc TNFR

Sphingosine-1-phosphate inhibits H2O2-induced granulosa cell apoptosis via the PI3K/Akt signaling pathway Tatsuo Nakahara, M.D., Akira Iwase, M.D., Ph.D.,

Expression and Function of RIG-I in Oral Keratinocytes and Fibroblasts

Inhibition of Notch Signaling Promotes the Adipogenic Differentiation of Mesenchymal Stem Cells Through Autophagy Activation and PTEN-PI3K/AKT/mTOR Pathway.

L.-H. Weng, C.-J. Wang, J.-Y. Ko, Y.-C. Sun, Y.-S. Su, F.-S. Wang

Volume 147, Issue 4, Pages (October 2014)

Estrogen enhancement of SGK1 expression induced by urocortin contributes to its cardioprotection against ischemia/reperfusion insult Binhai Cong, Jiankui.

Apoptosis-targeted therapies for cancer

Uc.454 Inhibited Growth by Targeting Heat Shock Protein Family A Member 12B in Non- Small-Cell Lung Cancer Jun Zhou, Chenghai Wang, Weijuan Gong, Yandan.

Caspase-1 from myeloid cells induces tumor proliferation via MyD88 oncogenic signaling. Caspase-1 from myeloid cells induces tumor proliferation via MyD88.

SOX4 Promotes Proliferative Signals by Regulating Glycolysis through AKT Activation in Melanoma Cells Wei Dai, Xinyuan Xu, Shuli Li, Jingjing Ma, Qiong.

Estrogenic regulation of testicular expression of stem cell factor and c-kit: implications in germ cell survival and male fertility Sara Correia, M.S.,

Relative protein levels

Cell Communication (Signaling) Part 3

Volume 41, Issue 4, Pages (February 2004)

J.P O'Rourke, H Hiraragi, K Urban, M Patel, J.C Olsen, B.A Bunnell

Supplementary Fig. S1 BCL2 5’flanking ctrl siRNA luc

Apoptosis-targeted therapies for cancer

GRM7 Regulates Embryonic Neurogenesis via CREB and YAP

Change in mRNA expression of Glasso network genes in differentiated PC12 cells following Caprin2 knockdown or Caprin2 overexpression. Change in mRNA expression.

Volume 41, Issue 6, Pages (December 2004)

Cell Communication (Signaling) Part 3

Volume 39, Issue 6, Pages (September 2010)

AKT2, but not AKT1, is required for regulating survival of PTEN-deficient prostate tumor spheroids. AKT2, but not AKT1, is required for regulating survival.

Transfection of stable β-catenin (S33Y) increased nuclear β-catenin and phosphorylated Akt expression (A) and reduced the promoting effect of HG on caspase-3.

Knockdown efficiency of different shRNAs.

BAK oligomerization in cells treated by UV is

Gold Nanoparticles for BCR-ABL1 Gene Silencing: Improving Tyrosine Kinase Inhibitor Efficacy in Chronic Myeloid Leukemia Raquel Vinhas, Alexandra R.

Volume 44, Issue 2, Pages (February 2006)

Fig. 4 Pathological features of c9FTD/ALS correlate with SUPT4H1 and SUPT5H expression in patient brain tissue, and partial knockdown of SUPT4H1 in C9orf72.

Fig. 3. BCL11A acts as a silencer of γ-globin gene expression, based on modulation of BCL11A levels. BCL11A acts as a silencer of γ-globin gene expression,

Fig. 4. Impaired induction of TH-response genes in trβ crispants

Fig. 3. Effects of Tec on IL-1β-induced apoptosis in chondrocytes.

Silencing Socs1 in the LLC line confers increased response to IFNγ in vitro and in vivo. Silencing Socs1 in the LLC line confers increased response to.

BCL-3 regulates expression of stemness-associated Wnt targets.

Lesley-Ann Martin, Mitch Dowsett Cancer Cell

Fig. 6 RUNX/CBFB interaction inhibitor, Ro5-3335, significantly decreases mouse neurofibroma growth in vivo. RUNX/CBFB interaction inhibitor, Ro5-3335,

B7-H1–induced reverse signals in myeloma cells.

The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells.

Fig. 8 C9orf72 knockdown results in an increase in autophagic flux.

TYK2 signaling in T-ALL. TYK2 signaling in T-ALL. TYK2 activates STAT1 through phosphorylation downstream of the IL-10 receptor. Once phosphorylated, STAT.

Fig. 5 C9orf72 knockdown disrupts autophagy induction.

Presentation transcript:

Fig. 4. Effects of natriuretic peptide receptor 2 (NPR2) knockdown on cells apoptosis in mouse Leydig cells. (A) Relative mRNA expression of cell apoptosis related genes (Bcl-2, Bax, p53, and Caspase-3) in mouse Leydig cells transducted with shRNA-NPR2 lentivirus. (B) The phosphorylation of AKT in mouse Leydig cells transducted with shRNA-NPR2 lentivirus. (C) Caspase-3 activity in mouse Leydig cells transducted with shRNA-NPR2 lentivirus. (D) Relative protein expression of Bcl-2 and Bax in mouse Leydig cells transducted with shRNA-NPR2 lentivirus. The β-actin was used as internal control. The phosphorylation of AKT were normalized to that of total AKT. The results are presented as the mean±standard error of mean and are representative of three independent experiments. *p<0.05 and **p<0.01 compared with each corresponding group in the control. Fig. 4. Effects of natriuretic peptide receptor 2 (NPR2) knockdown on cells apoptosis in mouse Leydig cells. (A) Relative mRNA expression of cell apoptosis related genes (Bcl-2, Bax, p53, and Caspase-3) in mouse Leydig cells transducted with shRNA-NPR2 lentivirus. (B)… World J Mens Health. 2019 May;37(2):186-198. https://doi.org/10.5534/wjmh.180041