A BMPy Road for Venous Development

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A BMPy Road for Venous Development Lauren M. Goddard, Mark L. Kahn Developmental Cell Volume 42, Issue 5, Pages 435-436 (September 2017) DOI: 10.1016/j.devcel.2017.08.016 Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 1 Twist1 Coordinates Skull and Venous Development through BMP Signaling Twist1+ osteoprogenitor cells (Osteo-PCs) express BMP2 and BMP4 that act on venous endothelial cells during skull formation (beige). In human craniosynostosis, loss of osteo-PC Twist1 results in defective formation of both the skull and the associated cranial venous system (blue) without disturbing arterial development (red). Developmental Cell 2017 42, 435-436DOI: (10.1016/j.devcel.2017.08.016) Copyright © 2017 Elsevier Inc. Terms and Conditions