Physiological in vitro model for the study of host-microbiome interactions in BV. Transmission electron microscopy illustrates human vaginal epithelial.

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Physiological in vitro model for the study of host-microbiome interactions in BV. Transmission electron microscopy illustrates human vaginal epithelial cells colonized with one of the signature bacterial species of BV, Atopobium vaginae. Physiological in vitro model for the study of host-microbiome interactions in BV. Transmission electron microscopy illustrates human vaginal epithelial cells colonized with one of the signature bacterial species of BV, Atopobium vaginae. Epithelial cells show no signs of apoptosis. Bacteria appear as dense, dark, round bodies, intimately attached to the epithelial surface or taken up inside the epithelial cell cytosol. (Reprinted from reference 150 with permission of the publisher.)‏ Andrew B. Onderdonk et al. Clin. Microbiol. Rev. 2016; doi:10.1128/CMR.00075-15