Fig. 1. Changes in hippocampal matrix metalloproteinase-9 (MMP-9) and angiopoietin-2 (ANG-2) expression over time following bilateral common carotid artery.

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Fig. 1. Changes in hippocampal matrix metalloproteinase-9 (MMP-9) and angiopoietin-2 (ANG-2) expression over time following bilateral common carotid artery occlusion (BCCAo). (A) Schematic diagram of experimental procedure. (B) Representative western blot for MMP-9 (n=4) and ANG-2 (n=5). (C) Hippocampal MMP-9 levels were significantly increased at 1 week following BCCAo, compared to controls (*). Increased MMP-9 returned to control levels at 4 and 8 weeks (#). (D) Hippocampal ANG-2 also increased at 1 week following BCCAo (*), although its expression levels decreased to control levels at 8 weeks following BCCAo (#, ##). Fig. 1. Changes in hippocampal matrix metalloproteinase-9 (MMP-9) and angiopoietin-2 (ANG-2) expression over time following bilateral common carotid artery occlusion (BCCAo). (A) Schematic diagram of experimental procedure. (B) Representative western blot for MMP-9 (n=4) and… Exp Neurobiol. 2018 Aug;27(4):299-308. https://doi.org/10.5607/en.2018.27.4.299