Sequential treatment with 5‐aza‐2′‐deoxycytidine and deacetylase inhibitors reactivates HIV‐1 One night after cell purification, CD8+‐depleted PBMCs from.

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Presentation transcript:

Sequential treatment with 5‐aza‐2′‐deoxycytidine and deacetylase inhibitors reactivates HIV‐1 One night after cell purification, CD8+‐depleted PBMCs from 12 HIV‐negative donors were mock‐treated or treated with 5‐AzadC. Three days post‐treatment, 1/3 of medium was replaced and HDACIs were added to the cultures. Six days after 5‐AzadC treatment, WST‐1 assay was performed. Mock value was arbitrarily fixed at 100% for each individual. Means are indicated by a line. IF THIS IMAGE HAS BEEN PROVIDED BY OR IS OWNED BY A THIRD PARTY, AS INDICATED IN THE CAPTION LINE, THEN FURTHER PERMISSION MAY BE NEEDED BEFORE ANY FURTHER USE. PLEASE CONTACT WILEY'S PERMISSIONS DEPARTMENT ON PERMISSIONS@WILEY.COM OR USE THE RIGHTSLINK SERVICE BY CLICKING ON THE 'REQUEST PERMISSIONS' LINK ACCOMPANYING THIS ARTICLE. WILEY OR AUTHOR OWNED IMAGES MAY BE USED FOR NON-COMMERCIAL PURPOSES, SUBJECT TO PROPER CITATION OF THE ARTICLE, AUTHOR, AND PUBLISHER. EMBO Mol Med, Volume: 8, Issue: 2, Pages: 117-138, First published: 17 December 2015, DOI: (10.15252/emmm.201505557)