Mechanisms of Loss of Heterozygosity in Neurofibromatosis Type 1-Associated Plexiform Neurofibromas  Katharina Steinmann, Lan Kluwe, Reinhard E. Friedrich, Victor-Felix Mautner, David N. Cooper, Hildegard Kehrer-Sawatzki  Journal of Investigative Dermatology  Volume 129, Issue 3, Pages 615-621 (March 2009) DOI: 10.1038/jid.2008.274 Copyright © 2009 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 1 LOH analysis in 13 plexiform neurofibromas. Tumor acronyms are indicated above. In those seven tumors highlighted with gray rectangles, LOH was caused by a deletion according to MLPA. The markers located in the NF1 microdeletion interval are underlined. Black circles: LOH, white circle: no LOH, striped circles: marker not informative, and gray filled circle: not determined. Journal of Investigative Dermatology 2009 129, 615-621DOI: (10.1038/jid.2008.274) Copyright © 2009 The Society for Investigative Dermatology, Inc Terms and Conditions