Frequency of PR3-ANCA and MPO-ANCA positivity in ANCA-positive patients with a particular organ system involvement in an inception cohort of 502 ANCA vasculitis.

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Frequency of PR3-ANCA and MPO-ANCA positivity in ANCA-positive patients with a particular organ system involvement in an inception cohort of 502 ANCA vasculitis patients with MPA, GPA, or RLV evaluated at the University of North Carolina Kidney Center (excl... Frequency of PR3-ANCA and MPO-ANCA positivity in ANCA-positive patients with a particular organ system involvement in an inception cohort of 502 ANCA vasculitis patients with MPA, GPA, or RLV evaluated at the University of North Carolina Kidney Center (excluding patients with EGPA) (Modified from Lionaki et al. [5]). Organ groupings are not mutually exclusive. ‘No lung and no ENT’ has vasculitis in some other organs. Plus means there is vasculitis in an additional organ. EGPA, eosinophilic granulomatosis with polyangiitis; ENT, ear, nose and throat; GI, gastrointestinal tract; GPA, granulomatosis with polyangiitis; MPA, microscopic polyangiitis; MPO-ANCA, ANCA specific for myeloperoxidase; PR3-ANCA, PR3-ANCA, ANCA specific for proteinase 3; RLV, renal-limited vasculitis. J. Charles Jennette, and Patrick H. Nachman CJASN 2017;12:1680-1691 ©2017 by American Society of Nephrology