Mechanisms of allergic pulmonary eosinophilia in the mouse

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Presentation transcript:

Mechanisms of allergic pulmonary eosinophilia in the mouse Ted T. Kung, PhD, Dawn Stelts, BS, Jackie A. Zurcher, MS, Arthur S. Watnick, PhD, Howard Jones, Peter J. Mauser, PhD, Xiomara Fernandez, MS, Shelby Umland, PhD, William Kreutner, PhD, Richard W. Chapman, PhD, Robert W. Egan, PhD Journal of Allergy and Clinical Immunology Volume 94, Issue 6, Pages 1217-1224 (December 1994) DOI: 10.1016/0091-6749(94)90335-2 Copyright © 1994 Mosby, Inc. Terms and Conditions

FIG. 1 Eosinophil levels in various tissues after challenge of ovalbumin-sensitized mice. Journal of Allergy and Clinical Immunology 1994 94, 1217-1224DOI: (10.1016/0091-6749(94)90335-2) Copyright © 1994 Mosby, Inc. Terms and Conditions

FIG. 1 Eosinophil levels in various tissues after challenge of ovalbumin-sensitized mice. Journal of Allergy and Clinical Immunology 1994 94, 1217-1224DOI: (10.1016/0091-6749(94)90335-2) Copyright © 1994 Mosby, Inc. Terms and Conditions

FIG. 2 The effect of anti-IL-5 on mouse BAL eosinophilia after ovalbumin challenge. Journal of Allergy and Clinical Immunology 1994 94, 1217-1224DOI: (10.1016/0091-6749(94)90335-2) Copyright © 1994 Mosby, Inc. Terms and Conditions

FIG. 3 The mechanism of steroid inhibition of mouse BAL eosinophilia. Journal of Allergy and Clinical Immunology 1994 94, 1217-1224DOI: (10.1016/0091-6749(94)90335-2) Copyright © 1994 Mosby, Inc. Terms and Conditions

FIG. 3 The mechanism of steroid inhibition of mouse BAL eosinophilia. Journal of Allergy and Clinical Immunology 1994 94, 1217-1224DOI: (10.1016/0091-6749(94)90335-2) Copyright © 1994 Mosby, Inc. Terms and Conditions

FIG. 4 The effect of anti-IL-5 on mouse bone marrow eosinophil levels after ovalbumin challenge. Journal of Allergy and Clinical Immunology 1994 94, 1217-1224DOI: (10.1016/0091-6749(94)90335-2) Copyright © 1994 Mosby, Inc. Terms and Conditions

FIG. 5 BAL eosinophilia in W/WV, W/W+, and mast cell–reconstituted W/WV mice. Journal of Allergy and Clinical Immunology 1994 94, 1217-1224DOI: (10.1016/0091-6749(94)90335-2) Copyright © 1994 Mosby, Inc. Terms and Conditions