Histological diagnosis of renal osteodystrophy Tony Freemont  Kidney International  Volume 56, Pages S26-S30 (December 1999) DOI: 10.1046/j.1523-1755.1999.07318.x Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 1 Transiliac bone biopsy. (a) Three-dimensional reconstruction of part of a transiliac bone biopsy using a high energy X-ray source. (b) Microscope section prepared from the biopsy. Toluidine blue staining, magnification 100×. Kidney International 1999 56, S26-S30DOI: (10.1046/j.1523-1755.1999.07318.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 2 Two-dimensional representation of a circle (center) could be part of a three-dimensional sphere (left) or a three-dimensional cylinder (right). Kidney International 1999 56, S26-S30DOI: (10.1046/j.1523-1755.1999.07318.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 3 Diagram of 10 histologic sections through a piece of bone containing an osteoclast. Sections 3–9 include the levels through the osteoclast. Serial sections 6–8 all contain the osteoclast, whereas in step serial sections 1 and 6 the osteoclast is only present in 6. Kidney International 1999 56, S26-S30DOI: (10.1046/j.1523-1755.1999.07318.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 4 Unstained histological section viewed in UV light. The tetracycline appears bright. Various artefacts caused by sectioning are seen in the biopsy, including effects due to oblique sectioning. (Original magnification ×200). Kidney International 1999 56, S26-S30DOI: (10.1046/j.1523-1755.1999.07318.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 5 Section of bone viewed in polarized light to show one way of identifying resorption surfaces. (Original magnification ×250). Kidney International 1999 56, S26-S30DOI: (10.1046/j.1523-1755.1999.07318.x) Copyright © 1999 International Society of Nephrology Terms and Conditions