ADA type 2 diabetes glycemic control algorithm, reproduced with permission from ref. 4. *Usually a basal insulin (neutral protamine Hagedorn, glargine, detemir, or degludec). ADA type 2 diabetes glycemic control algorithm, reproduced with permission from ref. 4. *Usually a basal insulin (neutral protamine Hagedorn, glargine, detemir, or degludec). DDP-4, dipeptidyl peptidase-4; DPP-4-i, DPP-4 inhibitor; fxs, fractures; GI, gastrointestinal; GLP-1 RA, GLP-1 receptor agonist; GU, genitourinary; HF, heart failure; hypo, hypoglycemia; SGLT2, sodium–glucose cotransporter 2; SGLT2-i, SGLT-2 inhibitor; SU, sulfonylurea; TZD, thiazolidinedione. Debbie Hinnen, and Jodi Strong Diabetes Spectr 2018;31:145-154 ©2018 by American Diabetes Association