Michael Navitsky, Abhinay D. Joshi, Michael D. Devous, Michael J

Slides:



Advertisements
Similar presentations
2015 Alzheimer's disease facts and figures Alzheimer's & Dementia: The Journal of the Alzheimer's Association Volume 11, Issue 3, Pages (March.
Advertisements

Sleep disruption changes across the disease trajectory: Pilot findings from the healthy patterns sleep study Nancy A. Hodgson, Albert J. Safi Alzheimer's.
Capillary dysfunction in Alzheimer's disease
DIAGNOSTIC ACCURACY AND CONFIDENCE IN THE CLINICAL DETECTION OF COGNITIVE IMPAIRMENT IN EARLY-STAGE PARKINSON’S DISEASE  Kathryn A. Wyman-Chick, Phillip.
Vladimir S. Fonov, Mahsa Dadar, Xiao Yiming, D. Louis Collins 
Relationship between Microstructural Degeneration of the Corpus Callosum, White Matter Hyperintensities, and Motor Function in Cognitively Intact Elderly 
Hilkka Liedes, Jyrki Lötjönen, Gerald P. Novak, Mark Forrest Gordon 
Comparison of accelerated and nonaccelerated MRI in ADNI: Effects on measures of brain and ventricular volumes and rates of atrophy  Kelvin Leung, Casper.
Different pathways to Alzheimer’s disease
A SYSTEMATIC REVIEW AND META-ANALYSIS COMPARING QUALITY-OF-LIFE RATINGS FROM FAMILY AND PAID CAREGIVERS OF PEOPLE WITH DEMENTIA RESIDING IN CARE HOMES 
Mutation frequency of pathogenic genes in familial Alzheimer’s disease in China  Jianping Jia, Liyong Wu, Wei Qin, Dan Li, Luxi Shen, Hanzhi Li, Qianqian.
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Trajectory of multi-dimensional caregiving burden in chinese informal caregivers for dementia: Evidence from exploratory and confirmatory factor analysis.
Interaction network of tau protein, beta-amyloid protein, and amyloid protein precursor under oxidative stress in Alzheimer’s disease  Eduardo de Souza/S.
INCREASED CSF LEVELS OF BIOMARKERS FOR NEURODEGENERATION IN FTLD-GRN MUTATION CARRIERS  Joery Goossens, Sara Van Mossevelde, Tobi Van den Bossche, Anne.
SERUM NEUROFILAMENT LIGHT PROTEIN PREDICTS CLINICAL OUTCOME IN TRAUMATIC BRAIN INJURY  Pashtun Shahim, Magnus Gren, Victor Liman, Ulf Andreasson, Niklas.
The differential diagnosis of amnestic mild cognitive impairment and Alzheimer's disease dementia by hippocampal volume measurement with MR in a chinese.
Localization of Hippocampal atrophy in Alzheimer's disease
INVESTIGATION OF 99MTC-LABELED CLIOQUINOL DERIVATIVE ON AMYLOID PLAQUE SPECIFICITY BY USING AN ANIMAL MODEL OF ALZHEIMER'S DISEASE  Ayfer Yurt KIlçar,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Christine Bredfeldt, Kristen Rice, Lisa Alecxih 
KETOGENIC DIET EFFECTS ON BRAIN KETONE METABOLISM AND ALZHEIMER'S DISEASE CSF BIOMARKERS  Suzanne Craft, Bryan J. Neth, Akiva Mintz, Kiran Sai, Nora Shively,
The effect of using a conditional discrimination procedure to teach name-face relation to a person diagnosed with dementia  Hanna S. Steingrimsdottir,
Alzheimer's disease biomarker-based clusters predict amyloid accumulation and cognitive decline in a preclinical cohort: Findings from the wisconsin registry.
Application of Resource Utilization in Dementia (RUD) instrument in a global setting  Anders Wimo, Anders Gustavsson, Linus Jönsson, Bengt Winblad, Ming-Ann.
LATENT-FACTOR STRUCTURE OF THE DELCODE STUDY NEUROPSYCHOLOGICAL TEST BATTERY  Steffen Wolfsgruber, Luca Kleineidam, Jannis Guski, Oliver Peters, Katharina.
APOE GENOTYPE MODIFIES THE EFFECTS OF AEROBIC TRAINING ON BRAIN GLUCOSE METABOLISM IN SUBJECTS WITH MILD COGNITIVE IMPAIRMENT  Fabio H.G. Porto, Artur.
HYPERGLYCEMIA: PREDISPOSITION FOR MICROEMBOLI, STROKE, AND WHITE MATTER CHANGES  Leila Parand, Saif Bushnaq, Yue Wang, Lenora Mathes, Dinesh Jillella,
Marjolein Bulk, Linda van der Graaf, Walid M
Cerebral amyloid angiopathy, neurodegeneration, and dementia in a population-based study on the very elderly Finns (Vantaa 85+)  Maarit Tanskanen, Mira.
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Japanese brain bank network for neuroscience research
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
BIOLOGICAL PATHWAYS FOUND IN COMMON BETWEEN ALZHEIMER’S DISEASE AND MAJOR DEPRESSION: A STUDY ON MICRORNA EXPRESSION IN A SYSTEMATIC REVIEW  Ana Paula.
Community environment and incident dementia: Results from the three-city study  Claudine Berr, Laure Anne Gutierrez, Sylvaine Artero, Catherine Helmer,
Pairwise gene-protein association analysis on CSF proteomics in the ADNI-1 cohort  Sungeun Kim, Shanker Swaminathan, Kwangsik Ngo, Shannon Risacher, Li.
Effect of hypertension and antihypertensive medication on executive function, brain atrophy, and white matter hyperintensities  Shannon L. Risacher, Li.
Application of Resource Utilization in Dementia (RUD) instrument in a global setting  Anders Wimo, Anders Gustavsson, Linus Jönsson, Bengt Winblad, Ming-Ann.
Longitudinal uncoupling of cerebral perfusion, glucose metabolism, and tau deposition in Alzheimer's disease  Antoine Leuzy, Elena Rodriguez-Vieitez,
LIFESPAN OF ONE FOCUSED ULTRASOUND MEDIATED BLOOD-BRAIN BARRIER TREATMENT IN A MOUSE MODEL OF ALZHEIMER'S DISEASE  Charissa Poon, Kullervo Hynynen  Alzheimer's.
The influence of biological and technical factors on quantitative analysis of amyloid PET: Points to consider and recommendations for controlling variability.
Summary of the evidence on modifiable risk factors for cognitive decline and dementia: A population-based perspective  Matthew Baumgart, Heather M. Snyder,
LINKING GENE PATHWAYS AND BRAIN ATROPHY IN ALZHEIMER'S DISEASE
Shruti Mishra, Brian Andrew Gordon, Karl A
Comparison of visual and quantitative florbetapir-PET reads in subjects with early Alzheimer's disease for assessing amyloid burden  Bradley Wyman, Yahong.
Sulantha S. Mathotaarachchi, Tharick A
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
The incremental diagnostic value of 18F-florbetapir imaging in naturalistic patients with cognitive impairment: The India-FBP study  Marina Boccardi,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Added value of 11C-PiB-PET imaging in the diagnosis of Alzheimer's disease  Kristian Frederiksen, Anne-Mette Hejl, Ian Law, Steen Hasselbalch, Gunhild.
Mark D. Meadowcroft, Douglas G. Peters, Carson J
COGNITIVE COMPLAINTS IN OLDER ADULTS AT RISK FOR ALZHEIMER’S DISEASE ARE ASSOCIATED WITH ALTERED RESTING STATE NETWORKS  Joey A. Contreras, Joaquín Goñi,
Distinct [18F]AV1451 retention patterns in clinical variants of Alzheimer’s disease  Rik Ossenkoppele, Daniel Schonhaut, Suzanne Baker, Andreas Lazaris,
MR-less cortical surface-projection of PET images from 11C- and 18F-labeled radiotracers  Vincent Doré, Pierrick Bourgeat, Luping Zhou, Jurgen Fripp,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
GREY MATTER CONNECTIVITY IS ASSOCIATED WITH CLINICAL PROGRESSION IN NON-DEMENTED, AMYLOID POSITIVE PATIENTS  Betty M. Tijms, Mara ten Kate, Sander C.J.
Cerebral hypoperfusion is not associated with an increase in amyloid β pathology in middle-aged or elderly people  Oskar Hansson, Sebastian Palmqvist,
DIFFERENCES IN ANALYTICAL SELECTIVITY OF β-AMYLOID (1-42) IMMUNOASSAYS EXPLAIN DISCORDANT RESULTS IN STUDY COMPARISONS  Hugo Marcel Vanderstichele, Emeric.
Alzheimer's Association towards Guidelines for Dementia Care Practice: Recommendations with emphasis on high-quality, person-centered care in long-term.
Brain amyloid deposition and metabolism in early and late mild cognitive impairment  Jared Rowley, Liyong Wu, Sara Mohades, Marina Dauar, Antoine Leuzy,
Tharick A. Pascoal, Sulantha S
Different pathways to Alzheimer’s disease
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
INTRINSIC CONNECTIVITY NETWORKS IN POSTERIOR CORTICAL ATROPHY: A ROLE FOR THE PULVINAR?  Carolyn A. Fredericks, Jesse Brown, Jersey Deng, Rik Ossenkoppele,
Automated detection of beta-amyloid–related cortical and subcortical signal changes in a transgenic model of Alzheimer's disease using high-field MRI 
Extracting white matter hyperintensities in Alzheimer's disease risk and aging studies using supervised segmentation methods  Vamsi Ithapu, Vikas Singh,
BRAIN AMYLOIDOSIS AND COGNITIVE DECLINE IN MCI: 12-MONTH FOLLOW-UP
ONE-YEAR GLOBAL OUTCOME OF A COMPREHENSIVE, INDIVIDUALIZED, PERSON CENTERED MANAGEMENT (CI-PCM) PROGRAM + MEMANTINE IN ADVANCED AD: A RANDOMIZED CONTROLLED.
Bistra Iordanova, Matthew C. Murphy, William E. Klunk, Alberto L
Presentation transcript:

CONVERSION OF AMYLOID QUANTITATION WITH FLORBETAPIR SUVR TO THE CENTILOID SCALE  Michael Navitsky, Abhinay D. Joshi, Michael D. Devous, Michael J. Pontecorvo, Ming Lu, William E. Klunk, Christopher C. Rowe, Dean F. Wong, Mark A. Mintun  Alzheimer's & Dementia: The Journal of the Alzheimer's Association  Volume 12, Issue 7, Pages P25-P26 (July 2016) DOI: 10.1016/j.jalz.2016.06.032 Copyright © 2016 Terms and Conditions

Figure 1a SUVr for 46 subjects of mixed amyloid pathology who were scanned with both florbetapir and PiB. Alzheimer's & Dementia: The Journal of the Alzheimer's Association 2016 12, P25-P26DOI: (10.1016/j.jalz.2016.06.032) Copyright © 2016 Terms and Conditions

Figure 1b Centiloids for 46 subjects obtained by linear regression through Figure 1a. Alzheimer's & Dementia: The Journal of the Alzheimer's Association 2016 12, P25-P26DOI: (10.1016/j.jalz.2016.06.032) Copyright © 2016 Terms and Conditions