LD structure of the TOX3/LOC region in HapMap CEU and YRI populations.

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LD structure of the TOX3/LOC643714 region in HapMap CEU and YRI populations. LD structure of the TOX3/LOC643714 region in HapMap CEU and YRI populations. LD structure was assessed using LD units (LDU) estimated with the SNPBrowser software (25). LD units are proportional to the decay of LD along the physical distance. Regions of constant (“flat”) LD units represent LD blocks. Note that the big block (from 51.09 to 51.18 Mb) that covers parts of the TOX3 and LOC643714 genes in the HapMap CEU population and it is split into smaller blocks and gaps in the HapMap YRI population. Edward A. Ruiz-Narváez et al. Cancer Epidemiol Biomarkers Prev 2010;19:1320-1327 ©2010 by American Association for Cancer Research