The use of arrays in preimplantation genetic diagnosis and screening

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The use of arrays in preimplantation genetic diagnosis and screening Joyce C. Harper, Ph.D., Gary Harton, B.S. Fertility and Sterility Volume 94, Issue 4, Pages 1173-1177 (September 2010) DOI: 10.1016/j.fertnstert.2010.04.064 Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

Figure 1 (A) Metaphase CGH and (B) array CGH. First the biopsied material undergoes WGA and the embryonic DNA is labeled in green fluorescence. A control sample is labeled in red fluorescence. The samples are then cohybridized onto either (A) a metaphase spread or (B) an array platform. In both cases, a computer analyzes the ratio of red-to-green fluorescence. Courtesy of Thalia Mamas and Leoni Xanthopoulou, University College London Centre for PG&D. Fertility and Sterility 2010 94, 1173-1177DOI: (10.1016/j.fertnstert.2010.04.064) Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions