Radiation resistance and stem-like cells in brain tumors

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Radiation resistance and stem-like cells in brain tumors Dolores Hambardzumyan, Massimo Squartro, Eric C. Holland Cancer Cell Volume 10, Issue 6, Pages 454-456 (December 2006) DOI: 10.1016/j.ccr.2006.11.008 Copyright © 2006 Elsevier Inc. Terms and Conditions

Figure 1 Stem-like cells in brain tumors Immunofluorescence images of fresh-frozen sections of a human medulloblastoma showing localized regions of cells expressing the stem cell markers nestin (green) and Notch receptor (red) that work well in histochemical staining. Nuclei are stained blue with DAPI. Note that these stem-like cells are located in a specific region, or niche, rather than distributed randomly throughout the tumor. Scale bar, 20 μm. Cancer Cell 2006 10, 454-456DOI: (10.1016/j.ccr.2006.11.008) Copyright © 2006 Elsevier Inc. Terms and Conditions