Effect of grass sublingual tablet immunotherapy is similar in children and adults: A Bayesian approach to design pediatric sublingual immunotherapy trials

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Presentation transcript:

Effect of grass sublingual tablet immunotherapy is similar in children and adults: A Bayesian approach to design pediatric sublingual immunotherapy trials Amarjot Kaur, PhD, David Skoner, MD, Joseph Ibrahim, PhD, Qing Li, PhD, Richard F. Lockey, MD, Michael Blaiss, MD, Albrecht Bufe, MD, Jens Strodl Andersen, PhD, Giorgio Walter Canonica, MD, Hendrik Nolte, MD, PhD Journal of Allergy and Clinical Immunology Volume 141, Issue 5, Pages 1744-1749 (May 2018) DOI: 10.1016/j.jaci.2017.09.051 Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Summary by age of mean change from baseline in log10 IgG4 levels at the end of the season in pooled timothy grass SLIT-tablet trials. n, Number of subjects with IgG4 at the end of the season. Journal of Allergy and Clinical Immunology 2018 141, 1744-1749DOI: (10.1016/j.jaci.2017.09.051) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Summary by age of mean change from baseline in IgE-blocking factor at the end of the season in pooled timothy grass SLIT-tablet trials. n, Number of subjects with IgE-blocking factor at the end of the season. Journal of Allergy and Clinical Immunology 2018 141, 1744-1749DOI: (10.1016/j.jaci.2017.09.051) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions