*P < 0.05; †P < The experiments were repeated 5 times.

Slides:



Advertisements
Similar presentations
Sensitization to Allergen Requires sufficient exposure (concentration and time) Requires genetic predisposition.
Advertisements

Fig. 3. IL-4, IFN-γ, and IL-17 production from α-GalCer-stimulated iNKT cells following FlaB treatment of PBMC cultures from asthma patients and healthy.
Food Protein-Induced Non-Immunoglobulin E-Mediated Allergic Colitis in Infants and Older Children: What Cytokines Are Involved? Int Arch Allergy Immunol.
Figure. Changes in the proportion of AD and exclusive breast-feeding in children at 1 to 3 years of age (KNHANES-IV and V, ). This survey was.
Fig. 1. Algorithm for diagnosis and treatment of hypereosinophilia
Fig. 1. The distribution of serum anti-dust EV IgG concentrations in the healthy control, asthma, COPD, and lung cancer groups. The dashed vertical line.
Fig. 2. Comparison of the Th1/Th2 ratio and the percentages of Th1 and Th2 cells between normal and allergic individuals. (A) The Th1/Th2 ratio observed.
Fig. 2. IgE Immunoblotting analysis with pooled sera of egg-allergic patients. (A) shows an immunoblot result using native serum. (B) is a immunoblot result.
Fig. 2. Effect of PGE2 on VEGF production in NPDFs as determined by RT-PCR (A, C) and ELISA (B, D). (A, B) RT-PCR and ELISA showed that the relative ratio.
From: Glucose Infusion Suppresses Surgery-induced Muscle Protein Breakdown by Inhibiting Ubiquitin-proteasome Pathway in Rats Anesthes. 2009;110(1):81-88.
Activation of NK cells during the early stage of allergic and fibrotic lung inflammation. Activation of NK cells during the early stage of allergic and.
The epidemiology of the atopic child
IL-4 induces IL-13–independent allergic airway inflammation
The role of viruses in acute exacerbations of asthma
Cigarette smoke extract induces thymic stromal lymphopoietin expression, leading to TH2-type immune responses and airway inflammation  Yuki Nakamura,
Thomas F. Tedder, PhD, Takashi Matsushita, MD, PhD 
Michael Biermer, Thomas Berg  Gastroenterology 
The histamine-cytokine network in allergic inflammation
Prostaglandin E2 suppresses allergic sensitization and lung inflammation by targeting the E prostanoid 2 receptor on T cells  Zbigniew Zasłona, PhD, Katsuhide.
Hepatitis C virus and interferon type III (interferon-λ3/interleukin-28B and interferon-λ4): genetic basis of susceptibility to infection and response.
Prostaglandin E2 suppresses allergic sensitization and lung inflammation by targeting the E prostanoid 2 receptor on T cells  Zbigniew Zasłona, PhD, Katsuhide.
Charles E. Reed, MD, Hirohito Kita, MD 
Volume 140, Issue 1, Pages (January 2011)
Update on the role of prostaglandins in allergic lung inflammation: Separating friends from foes, harder than you might think  Martin L. Moore, PhD, R.
Cockroach proteases increase IL-8 expression in human bronchial epithelial cells via activation of protease-activated receptor (PAR)–2 and extracellular-signal-regulated.
Liam O’Mahony, PhD, Mübeccel Akdis, MD, PhD, Cezmi A. Akdis, MD 
A.K.I. Kuroki, Masayuki Iyoda, Takanori Shibata, Tetsuzo Sugisaki 
Enhanced CD46-induced regulatory T cells suppress allergic inflammation after Dermatophagoides pteronyssinus–specific immunotherapy  Yi-Giien Tsai, MD,
Lung ILC2s link innate and adaptive responses in allergic inflammation
Fig. 4. Immunomodulation by TolDCs
Fig. 3. (A) Effect of EP receptor agonists on VEGF production by NPDFs
Fig. 2. Sera IgE reactivity patterns and the frequency of reactivity to raw and cooked shrimp extracts by Western blot. (A, C) All sera were diluted at.
Fig. 3. Reporter assay for the RS-ATL8 reporter cell line against shrimp extracts (A, B) RS-ATL8 cells were sensitized overnight with diluted pooled sera.
Fig. 5. Silencing of TAB2 mimics the effects of miR-155-5p on BSMCs
Fig. 7. Effect of capsazepine and TRPV1 siRNA on total collagen levels
Fig. 2. Effect of capsazepine and TRPV1 siRNA on total/differential cell counts in BAL fluid. Mice were sacrificed after measurement of AHR, and BAL was.
Fig. 5. (A) The effect of PKA and PI3K inhibitors on VEGF production in NPDFs. KT5720 and LY significantly decreased VEGF production. (B) The effect.
Fig. 4. (A) The effect of PGE2 on cAMP release
Fig. 6. Mucus analysis of lungs from allergic and tolerized mice
Fig. 2. GCE induces allergic inflammation in the mouse model of asthma
Interleukin-1 blockade effects interferon (IFN)-γ production by multiple cell types. a) Gating strategy for flow cytometry: CD56+ natural killer (NK) cells.
Fig. 2. Binding of specific IgE to D20110 and S47W
Fig. 5. Effect of capsazepine and TRPV1 siRNA on goblet cell hyperplasia in lung tissues. (A) The paraffin-embedded tissues were cut into 5- to 6-µm-thick.
Fig. 4. Levels of serum total IgE and IgE concentrations secreted into supernatants of the PBMCs cultured for 3, 5, and 7 days the AR patients and the.
Fig. 2. Putative mechanisms of oral tolerance induction in the gut
Figure. Factors that can influence the severity of RV infections and the risk of RV-induced exacerbations of asthma. In children and adults with asthma,
Fig. 1. Treatment with IL-13 induces proliferation and migration of BSMCs. (A) MTT assay was performed to evaluate the effects of IL-13 on the proliferation.
*P < 0.01; †P < The experiments were repeated 5 times.
*P < 0.01; †P < The experiments were repeated 5 times.
*P < 0.01 and †P < The experiments were repeated 6 times.
Systemic and localized seminal plasma hypersensitivity patients exhibit divergent immunologic characteristics  Debajyoti Ghosh, PhD, Jonathan A. Bernstein,
Supplementary Fig. S1. A summary of the suggested mechanism underlying asthma. PAR2, activated by a protease-containing allergen, induces the generation.
Figure 1. Cross talk between the immune system and osteoclasts in osteoclastogenesis. Osteoclasts are derived from monocyte precursor cells. RANKL from.
Nrf2 activation by sulforaphane restores the age-related decrease of TH1 immunity: Role of dendritic cells  Hyon-Jeen Kim, PhD, Berenice Barajas, BS,
*P < The experiments were repeated 5 times.
Fig. 2. The factors involved in acidic pH maintenance and their role in normal epidermis, and the consequences of altered pH in patients with AD. (A) Exogenous.
Fig. 4. The expression of TRAF6 in the PBMCs of the AR children after a 3-month SIT treatment. (A) Representative Western blot analysis of TRAF6 in the.
Fig. 1. Levels of Th2 and Th17 cytokines in HDM-induced mouse model of asthma. (A) The design of the HDM-induced mouse model of asthma. (B) The numbers.
Fig. 4. The inhibition of mast cell infiltration by topical application of the TECA + AST combination in dorsal ear and back skin. Mast cell infiltrations.
Fig. 1. Differences in body weight, dorsal ear skin thickness and phenotypes, as well as back skin phenotypes. Body weights of mice in the 5 groups were.
Fig. 2. Effect of activated vitamin D on immune cells
Supplementary Fig. S5. Protein profiles in the DIA set
Supplementary Fig. S2. Profile plot of the proteomics analysis
Fig. 1. Immunohistochemical staining for TMEM16A and MUC5AC in human sinonasal epithelium: TMEM16A and MUC5AC proteins in human nasal polyp epithelium.
Fig. 1. Protein analysis of the German cockroach extracts
Fig. 3. Structural equation modeling to estimate relationships among K-UCT and UAS7/CU-QoL/salivary cortisone levels. The K-UCT was found to be a significant.
Fig. 2. (A) Results of real-time polymerase chain reaction (PCR) of neuropeptide Y (NPY) and its receptors. Among all ligands and receptors, NPYR1 was.
Fig. 1. Chest X-ray taken during the patient's first admission demonstrates opacities in the right middle lobe and right lower lobe, suggesting pneumonia.
Fig. 5. Effects of IL-9 blockade on chronic pulmonary inflammation
Fig. 5. Can f 4-specific mAbs and the sandwich ELISA for the quantification of Can f 4. (A) The epitope specificity of the three Can f 4-specific mAbs.
Presentation transcript:

*P < 0.05; †P < 0.01. The experiments were repeated 5 times. Fig. 3. GCE induces T helper 2-allergic inflammation in a mouse model of asthma. The levels of IL-4 and IL-13 are significantly increased following GCE treatment and suppressed following PAR2-ant and NAC treatment in the lung (A and C). Moreover, the level of IFN-ν is significantly decreased following GCE treatment and increased following PAR2-ant and NAC treatment (B). Data were measured using real-time polymerase chain reaction. GCE, German cockroach extract; IL, interleukin; IFN, interferon; PAR2-ant, protease-activated receptor 2-antagonist; NAC, N-acetylcysteine. *P < 0.05; †P < 0.01. The experiments were repeated 5 times. Fig. 3. GCE induces T helper 2-allergic inflammation in a mouse model of asthma. The levels of IL-4 and IL-13 are significantly increased following GCE treatment and suppressed following PAR2-ant and NAC treatment in the lung (A and C). Moreover, the level of IFN-ν is significantly decreased following GCE treatment and increased following PAR2-ant and… Allergy Asthma Immunol Res. 2019 Jul;11(4):560-571. https://doi.org/10.4168/aair.2019.11.4.560