Volume 108, Issue 4, Pages 431-434 (February 2002) Nuclear RNA Turnover  Melissa J Moore  Cell  Volume 108, Issue 4, Pages 431-434 (February 2002) DOI: 10.1016/S0092-8674(02)00645-1

Figure 1 Nuclear Routes of Processing and Turnover for RNA Pol II Transcripts Nuclear processing of Pol II transcripts includes capping, excision of introns, and addition of a polyA tail. The nuclear RNA degradation machinery consists largely of exonucleases, the best characterized of which are the exosome and Rat1p. In addition to degrading excised introns, nuclear exonucleases appear to assist in the elimination of inefficiently processed pre-mRNAs and malformed mRNAs. Cell 2002 108, 431-434DOI: (10.1016/S0092-8674(02)00645-1)