IL-6 production with increasing doses of endotoxin.

Slides:



Advertisements
Similar presentations
Antitumor effect of the combination of IL-2 IC and anti–CTLA-4.
Advertisements

Treatment with BLU9931 leads to tumor regression in the FGF19-overexpressing PDX-derived xenograft LIXC012. Treatment with BLU9931 leads to tumor regression.
Sensitivity, specificity, positive predictive value, and negative predictive value for the different cutoffs used. Sensitivity, specificity, positive predictive.
Correlation between endogenous STAT5ab signaling and circulating plasma factors. Correlation between endogenous STAT5ab signaling and circulating plasma.
Tumor development of poorly immunogenic LLC and B16F10 cells modified to produce GM-CSF was markedly inhibited. Tumor development of poorly immunogenic.
Survival of mice after infection with M
Autoradiographs of cDNA gene array of regulatory genes from untreated control (column A) and quercetin-treated (column B) cells. Autoradiographs of cDNA.
Effect of quercetin on colony-forming abilities of prostate cancer cell lines with different aggressive potentials. Effect of quercetin on colony-forming.
SpA-SEA-D227A-induced CTL lyse MAb-coated EC
Treatment with BLU9931 leads to tumor regression in the FGF19-amplified Hep 3B liver cancer model. Treatment with BLU9931 leads to tumor regression in.
Effect of OPN on apoptosis of DCs
Ex vivo IL-6 production. Ex vivo IL-6 production. Human whole blood was stimulated with the indicated doses of the E. coli O113 endotoxin that was used.
Itraconazole tissue and fluid concentrations in humans as multiples of the maximal or simultaneously measured concentration in plasma (μg/ml) after systemic.
Survival of BALB/c mice after HK/Syd challenge.
Proinflammatory activities of Lactobacillus subcellular fractions.
Flow cytometry analysis of TNF-β- and IL-10-producing CD33+ cells.
Voriconazole tissue and fluid concentrations in humans as multiples of the maximal or simultaneously measured concentration in plasma (μg/ml) after systemic.
Hematological alterations after endotoxin injection.
Comparisons of small-volume RTx assay results to bDNA and TaqMan results for clinical serum and plasma specimens for quantification of HCV RNA. (A) Linear.
Comparison of relative activity of Adjuplex and other commonly used adjuvants. Comparison of relative activity of Adjuplex and other commonly used adjuvants.
Western blot results for serum samples obtained from experimentally vaccinated dogs prior to and at various times (weeks) following initial vaccination.
Kinetics of CXC chemokine appearance after endotoxin injection.
Profiles of anti-inflammatory cytokines after endotoxin injection.
Effect of route of administration (i.v. versus i.p.).
Effects of E. coli and S. aureus infection on levels of TNF-α and IL-1β in milk. Effects of E. coli and S. aureus infection on levels of TNF-α and IL-1β.
(A) CDK2 and p53 gene expression levels, as quantitated by real-time quantitative PCR with SYBR Green master mix (Stratagene, La Jolla, Calif.). (A) CDK2.
PCR amplification of the ORF encoding the cytosolic p36 protein of M
Fluconazole tissue and fluid concentrations in humans as multiples of the maximal or simultaneously measured concentration in plasma (μg/ml) after systemic.
Reproducibility of LPA results for cryopreserved PBMC after variable periods of storage in liquid nitrogen. Reproducibility of LPA results for cryopreserved.
Growth of B. dermatitidis yeast is inhibited by deferoxamine only at concentrations of 0.5 mM or greater. Growth of B. dermatitidis yeast is inhibited.
Intracellular TNF-α and IL-4 expression in gated CD33+ monocytes by three-color flow cytometry. Intracellular TNF-α and IL-4 expression in gated CD33+
(A) Mean glucose concentrations (standard error) over a 3-hour period in 21 placebo- and 15 pramlintide-treated patients with type 1 diabetes treated for.
The NTP increases tyrosine phosphorylation of PLC-γ1.
Immunization regimens that include a GLA-SE-formulated protein vaccine generate memory CD4 T cells. Immunization regimens that include a GLA-SE-formulated.
Schematic representation of the reactivities of IgM antibodies induced against Gly-Ala repeats of EBNA-1 and against glycine-rich motifs of HCMV antigens,
Comparison of OPN production by mature DCs and activated macrophages.
OPN mediates maturation from immature DCs to mature DCs
Reactivity of the anti-p36 MAbs against whole M
RTA-specific serum IgG antibody titers and TNA in mice immunized with RiVax or RVEc. RTA-specific serum IgG titers after the second (A) or third (B) immunizations.
Doses of trial medication in the liraglutide groups (A) and in the placebo groups (B). Doses of trial medication in the liraglutide groups (A) and in the.
Effects of intramammary infection with E. coli or S
Flow cytometry analysis of intracellular cytokine expression in control PBMC (left set of panels) and following either PMA-ionomycin activation (middle.
Dilution of anti-C6 monoclonal antibody shows the broader linear range of the Multiplex assay in comparison to standard ELISA. Shown is the dilution of.
Representative cytokine and cytotoxicity responses to CMV peptides on day 0 and day 7 in one HLA A2+ donor. Representative cytokine and cytotoxicity responses.
Eight weeks after primary i. n
Effect of HL60 cell age (expressed in cell passage) on opsonophagocytic activity. Effect of HL60 cell age (expressed in cell passage) on opsonophagocytic.
IgM-specific immunoblot analysis of different HCMV recombinant antigens with a selected serum sample from an HCMV-seronegative patient with acute EBV-induced.
Microcolonies of S. pneumoniae serotype 6B on a Todd-Hewitt agar-yeast extract plate with an overlay containing TTC and antibiotic after 18 h of incubation.
Dot plot comparison of EBNA-1 with recombinant antigens 52/3 (aa 297 to 433 of pUL44) and UL57/3 (aa 545 to 601 of pUL57) of HCMV, containing glycine-rich.
Mean weight change from original weight of (a) BALB/c (b) DBA/2 mice after one (♦) or two (▴) injections of 10 mg/kg and one (▪) or two (×) injections.
Expression of IFN-λs, IFN-λR1, and IL-10R2 in Xenopus tissues after stimulation in vivo with poly(I:C). Expression of IFN-λs, IFN-λR1, and IL-10R2 in Xenopus.
Group-averaged IL-10 levels (in pg/ml) from the Luminex assay for control, CFS with FM, and CFS without FM groups. Group-averaged IL-10 levels (in pg/ml)
Effect of MZ treatment on lung colony formation in an experimental metastasis. Effect of MZ treatment on lung colony formation in an experimental metastasis.
Effects of intramammary infection with E. coli or S
Flow cytometric gating strategy used to identify CD69 surface expression on CD4 (left paired columns) and CD8 (right paired columns) T lymphocytes. Flow.
Long-lived antibody-secreting cells in the bone marrow, induced by PfCelTOS vaccines containing various adjuvant formulations with emulsion doses of 0.02%
Long-lived antibody-secreting cells in the bone marrow, induced by PfCelTOS vaccines containing various adjuvant formulations with emulsion doses of 0.5%
Distributions of levels of antibodies to periodontal pathogens and plasma vitamin C concentrations. Distributions of levels of antibodies to periodontal.
Antigen-specific cytokine-producing cells (IFN-γ and IL-5) detected by ELISPOT assay 3 weeks after the 3rd immunization. Antigen-specific cytokine-producing.
Anti-PT IgG results from 227 patients with coughs of unknown etiology who reported the severity of cough on a scale from 0 to 10. Anti-PT IgG results from.
Acute circadian disruption alters ILC3 cytokine secretion.
Quantitation of apoptosis in M. aviumsubsp
Time to culling for all reasons among J5 vaccinates and controls
Immunoblot of scFv antibody detected with an anti-FLAG antibody.
OPN production by immature DCs and mature DCs treated with PAMPs
Mean reciprocal IFA titer results for serum samples from experimentally vaccinated animals. Mean reciprocal IFA titer results for serum samples from experimentally.
Amino acid sequence of antigenic fragments 52/3 and UL57/3 of pUL44 and pUL57, respectively, and sequence comparison by dot plot analysis. Amino acid sequence.
The NTP inhibits the AFC response to SRBC
Indirect immunofluorescence reactions on primate smooth muscle tissue for EMA detection depicting the following: (A) prozone reactions at low dilution.
Surface CD4 and CD14 and intracellular TNF-α expression in PBMCs
Presentation transcript:

IL-6 production with increasing doses of endotoxin. IL-6 production with increasing doses of endotoxin. Mice were injected with the indicated doses of endotoxin, and plasma was harvested 2 h later. Increasing doses of endotoxin resulted in increasing plasma IL-6 levels. Note that both the IL-6 concentration (Conc.) and endotoxin dose are plotted on a log scale. The line indicates the regression through the data. Shannon Copeland et al. Clin. Diagn. Lab. Immunol. 2005; doi:10.1128/CDLI.12.1.60-67.2005