T-Cell Memory: The Importance of Chemokine-Mediated Cell Attraction

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T-Cell Memory: The Importance of Chemokine-Mediated Cell Attraction Bernhard Moser  Current Biology  Volume 16, Issue 13, Pages R504-R507 (July 2006) DOI: 10.1016/j.cub.2006.06.008 Copyright © 2006 Elsevier Ltd Terms and Conditions

Figure 1 Leukocyte relocation in the course of MC virus infection. MC virus infection of keratinocytes within human epidermis initiates sequential leukocyte relocation steps involving: lymph node homing of antigen-presenting dendritic cells and naïve T cells; T cell–dendritic cell and T cell–B cell interactions in the T zone and B zone of the axillary lymph node; and relocation of newly generated, MC virus-specific effector T cells to the MC virus infection site. MC, molluscum contagiosum; DC, dendritic cell; iDC/mDC, immature/mature DC; Mϕ, macrophage; CD4-T/CD8-T, CD4+ T cell/CD8+ T cell; Effector-T, effector T cell ; TFH, follicular B helper T cell; B, B cell; Plasma-B, plasma cell; Ab, antibody; Inf-CR, receptors for inflammatory chemokines. Current Biology 2006 16, R504-R507DOI: (10.1016/j.cub.2006.06.008) Copyright © 2006 Elsevier Ltd Terms and Conditions