Kaplan-Meier curves for overall survival in patients with adenocarcinoma and time since first-line therapy of <9 months (A), all patients with adenocarcinoma.

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Kaplan-Meier curves for overall survival in patients with adenocarcinoma and time since first-line therapy of <9 months (A), all patients with adenocarcinoma (B) and the total population (C) from LUME-Lung 1. Kaplan-Meier curves for overall survival in patients with adenocarcinoma and time since first-line therapy of <9 months (A), all patients with adenocarcinoma (B) and the total population (C) from LUME-Lung 1. Patients without documented death were censored at the date of last contact when the patient was known to be alive. Adapted from Reck et al.25 Docetaxel plus nintedanib versus docetaxel plus placebo in patients with previously treated non-small-cell lung cancer (LUME-Lung 1): a phase 3, double-blind, randomised controlled trial. 143–155, Copyright (2014), with permission from Elsevier. Christian Manegold et al. ESMO Open 2016;1:e000118 Copyright © European Society for Medical Oncology. All rights reserved.