Extensive quantitative remodeling of the proteome between normal colon tissue and adenocarcinoma Abundance of proteins matching selected subcellular locations.

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Extensive quantitative remodeling of the proteome between normal colon tissue and adenocarcinoma Abundance of proteins matching selected subcellular locations (A–G) and functions (H–N). The numbers of proteins belonging to each class are given in the parentheses. The protein abundances were calculated on the basis of total spectral intensities of all quantified proteins. Red boxes indicate that the changes between cancer and normal were significant with P<0.01. Note that serum albumin levels (gray boxes) are similar between the three types of samples, indicating absence of differential contamination with plasma proteins. In (L), summed abundance of core and linker histones are shown by separate boxes. The purple boxes are for linker histones whereas the core histones by red boxes. IF THIS IMAGE HAS BEEN PROVIDED BY OR IS OWNED BY A THIRD PARTY, AS INDICATED IN THE CAPTION LINE, THEN FURTHER PERMISSION MAY BE NEEDED BEFORE ANY FURTHER USE. PLEASE CONTACT WILEY'S PERMISSIONS DEPARTMENT ON PERMISSIONS@WILEY.COM OR USE THE RIGHTSLINK SERVICE BY CLICKING ON THE 'REQUEST PERMISSIONS' LINK ACCOMPANYING THIS ARTICLE. WILEY OR AUTHOR OWNED IMAGES MAY BE USED FOR NON-COMMERCIAL PURPOSES, SUBJECT TO PROPER CITATION OF THE ARTICLE, AUTHOR, AND PUBLISHER. Mol Syst Biol, Volume: 8, Issue: 1, First published: 11 September 2012, DOI: (10.1038/msb.2012.44)