Comparison of the nADC value and CNR on T2-weighted images of 13 histologically confirmed brain lesions. Comparison of the nADC value and CNR on T2-weighted images of 13 histologically confirmed brain lesions. Most well differentiated adenocarcinomas (Well diff. AC) are distributed at high nADC and low CNR. One small-cell carcinoma (Small cell ca.) and 1 large cell neuroendocrine carcinoma (LCNC) were distributed at low nADC and high CNR. Poorly diff. AC indicates poorly differentiated adenocarcinoma; Large cell ca., large cell carcinoma; SCC, squamous cell carcinoma; Mucoepidermoid ca., mucoepidermoid carcinoma; Papillotubular ca., papillotubular carcinoma. Y. Hayashida et al. AJNR Am J Neuroradiol 2006;27:1419-1425 ©2006 by American Society of Neuroradiology