Structural classes of antimicrobial peptides.

Slides:



Advertisements
Similar presentations
Overview of potential risk or protective factors influencing the horizontal or vertical transmission of Neospora caninum and the occurrence of exogenous.
Advertisements

Itraconazole tissue and fluid concentrations in humans as multiples of the maximal or simultaneously measured concentration in plasma (μg/ml) after systemic.
Diagram of AmpC from E. coli complexed with acylated ceftazidime (PDB accession number 1IEL) (265) created with Cn3CD, version 4.1 (available at
Voriconazole tissue and fluid concentrations in humans as multiples of the maximal or simultaneously measured concentration in plasma (μg/ml) after systemic.
MIC distributions of selected β-lactam antimicrobial agents for H
Frequency of lesions detected using CNS imaging (computed tomography [CT] and magnetic resonance imaging [MRI]) on patients with baylisascariasis (see.
Characterization of oprD promoter elements.
Phylogenetic tree showing generic and species positions based on Bayesian analysis of the nuclear ribosomal DNA 28S region (1,200 bp) of Schistosomatidae.
Mechanisms of action of antibacterial peptides.
Columbia blood agar plate showing an isogenic S
Approximate numbers of cases per 100,000 individuals caused by penicillin resistance for each year (left). Approximate numbers of cases per 100,000 individuals.
MexT-associated downregulation of oprD expression.
Relative abundances of Propionibacterium species in different skin areas determined by 16S rRNA gene sequence analysis of 10 individuals. Relative abundances.
Glucose concentration-dependent increase of melanin synthesis.
Detection of Ebola virus infection in nonfatal versus fatal cases.
Increasing prevalence of multidrug resistance among P
Examples of changes in colony morphology that can occur with hVISA and VISA strains. Examples of changes in colony morphology that can occur with hVISA.
Structure of PrfA (A) and its target DNA sequences in PrfA-regulated promoters (B). Structure of PrfA (A) and its target DNA sequences in PrfA-regulated.
Positivity rates and concordance of multiplex PCR and blood culture (BC) results from 27 published studies. Positivity rates and concordance of multiplex.
Fluconazole tissue and fluid concentrations in humans as multiples of the maximal or simultaneously measured concentration in plasma (μg/ml) after systemic.
Number of outbreaks associated with drinking water by water system type and year (n = 780), 1971 to “Other” includes outbreaks associated with bottled.
Percentages of outbreak deficiencies (n = 671) in public water systems (n = 656) by time period, 1971 to 2006, excluding outbreaks associated with Legionella.
Schematic representation of signaling by KSHV LANA
Schematic representing the activation of the complement cascade.
Potentiation of legacy antibiotics against P
Phylogenetic network with concatenated 16S rRNA, 23S rRNA, groEL, rpoB, and dnaK sequences (3,009 unambiguously aligned base pairs), including 71 Coxiella-like.
Schematic diagram of the JCV genome.
Drug transport mechanism of AcrB.
Β-Lactam hydrolysis of cephalosporin followed by nonenzymatic release of a leaving group (LG). β-Lactam hydrolysis of cephalosporin followed by nonenzymatic.
(Top) Graph illustrating citations in books for Plasmodium falciparum and Plasmodium vivax from 1900 to 2008, generated by use of the tool at
Concentrations in tissues and body fluids for each systemic antifungal agent relative to its concentration in plasma. Concentrations in tissues and body.
Number of outbreaks associated with drinking water by system type and month (n = 762), 1971 to 2006, excluding outbreaks associated with commercially bottled.
Summary of the distribution and genetic context of the OXA-type enzymes in Acinetobacter baumannii. Summary of the distribution and genetic context of.
Fabrizio Dutly, and Martin Altwegg Clin. Microbiol. Rev. 2001; doi:10
Shell vial system protocols used for specific isolation of Bartonella, Coxiella burnetii, rickettsiae, or T. whipplei and for unspecific research into.
Staphylococcus aureus and Staphylococcus epidermidis cell surface proteins, known as microbial surface components recognizing adhesive matrix molecules.
Structure of cefiderocol (hybrid 10), previously known as S , derived by linking ceftazidime to the siderophore catechol 2-chloro-3,4-dihydroxybenzoic.
Examples of tobramycin-efflux pump hybrids: tobramycin linked to 1-(1-naphthylmethyl)-piperazine (NMP) (hybrid 14), tobramycin linked to paroxetine (hybrid.
Hector H. García et al. Clin. Microbiol. Rev. 2002; doi: /CMR
Illustration of a stably tethered structure made by the DNL method.
Publications on biosensors for the field in general compared with the specific detection of whole bacteria. Publications on biosensors for the field in.
Roberta B. Carey et al. Clin. Microbiol. Rev. 2018; doi: /CMR
Various possible courses of the immune response to severe sepsis and septic shock over 28 days. Various possible courses of the immune response to severe.
Schematic representation of 5′→3′ exonuclease cleavage of a 5′-labeled (small black star) probe with a 3′-phosphate (grey circle) extension blocker. Schematic.
Schematic description of sites of action of different antifungal agents. Schematic description of sites of action of different antifungal agents. Candins.
Stages of biofilm development (214).
Photomicrographs of six enteric protozoa.
(A) Crystal structure of the hemagglutinin (HA) trimer.
Percentages of outbreak deficiencies in public water systems associated with untreated and improperly treated source water by year, 1971 to 2006, excluding.
Giemsa-stained thin blood smears from a nonobese diabetic (NOD)-SCID mouse infected with (A) B. microtistrain MN1, (B) a hamster infected with B. microti.
Number of ESBL carriers in the community in 2010, according to WHO region grouping. Number of ESBL carriers in the community in 2010, according to WHO.
The Scorpions primer is an extension of molecular beacons.
Schematic diagram of the nuclear magnetic resonance-derived structure, posttranslational modifications of human PrPC, and epitopes of anti-PrP antibodies.
Phylogenetic trees for fusion (F) and attachment (G) genes of selected HMPV isolates. Phylogenetic trees for fusion (F) and attachment (G) genes of selected.
Fluconazole zone diameter distributions for all Candida spp
Adherence patterns of enteropathogenic E
Outcomes of infections caused by carbapenemase-producing Klebsiella pneumoniae, according to treatment regimen. Outcomes of infections caused by carbapenemase-producing.
Phylogenetic tree of the complete genomes of 27 representative human (black) and camel (red) MERS-CoV strains rooted by NeoCoV (KC ). Phylogenetic.
Cytokines and cytokine receptors involved in type I immunity in tuberculosis. Cytokines and cytokine receptors involved in type I immunity in tuberculosis.
Structures of T4 pilins and minor pilins.
Distribution of the four major molecular types of C
The Alp family of proteins.
Comparison of the van gene clusters.
Schematic representation of the relationships between acid resistance (urease activity and urea transport), nitrogen metabolism (ammonia production), metal.
IF2 and structural homologues.
Effects of acute malnutrition on lymphoid and hematopoietic organs.
(A) Crystal structure of the monomer of PGI/PMI from Pyb
Diagrammatic view of the locations of genes encoding classical HLA class I (HLA-A, -B, -C, -E, -F, and -G) and class II (DR, DQ, DP, and DM) molecules.
Proposed United Nations “One Health” framework.
Amino acid substitutions in SHV ESBL derivatives.
Presentation transcript:

Structural classes of antimicrobial peptides. Structural classes of antimicrobial peptides. (A) Mixed structure of human β-defensin-2 (PDB code 1FQQ) (216); (B) looped thanatin (PDB code 8TFV) (156); (C) β-sheeted polyphemusin (PDB code 1RKK) (202); (D) rabbit kidney defensin-1 (PDB code 1EWS) (165); (E) α-helical magainin-2 (PDB code 2MAG) (76); (F) extended indolicidin (PDB code 1G89) (212). The disulfide bonds are indicated in yellow, and the illustrations have been prepared with use of the graphic program MolMol 2K.1 (132). Håvard Jenssen et al. Clin. Microbiol. Rev. 2006; doi:10.1128/CMR.00056-05