The Brain Uses Mostly Dissolved Oxygen During Profoundly Hypothermic Cardiopulmonary Bypass Franklin Dexter, MD, PhD, Frank H Kern, MD, Bradley J Hindman,

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Presentation transcript:

The Brain Uses Mostly Dissolved Oxygen During Profoundly Hypothermic Cardiopulmonary Bypass Franklin Dexter, MD, PhD, Frank H Kern, MD, Bradley J Hindman, MD, William J Greeley, MD The Annals of Thoracic Surgery Volume 63, Issue 6, Pages 1725-1729 (June 1997) DOI: 10.1016/S0003-4975(97)00297-X

Fig. 1 Percent of cerebral oxygen delivery in dissolved form (ie, percent of arterial oxygen content) versus arterial oxygen partial pressure (PaO2) and hemoglobin concentration. Hemoglobin concentration (along the top of the plot) has units of grams per 100 milliliters. The Annals of Thoracic Surgery 1997 63, 1725-1729DOI: (10.1016/S0003-4975(97)00297-X)

Fig. 2 Fraction of oxygen consumed by the brain obtained from dissolved oxygen versus percentage of oxygen delivered to the brain in dissolved form, nasopharyngeal temperature, and pump flow rate. Measurements represented by open and filled circles correspond to “full” (>70 mL · kg−1 · min−1) and “low” (70 mL · kg−1 · min−1) pump flow rates. The percentage of cerebral oxygen delivery (CMRO2) in dissolved form can be related to hemoglobin concentration and arterial oxygen partial pressure using Fig. 1. The Annals of Thoracic Surgery 1997 63, 1725-1729DOI: (10.1016/S0003-4975(97)00297-X)