Expression profile of RSPO1 and 2 in gastric cancer.

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Expression profile of RSPO1 and 2 in gastric cancer. Expression profile of RSPO1 and 2 in gastric cancer. During tumorigenesis, expression of RSPO1 (A–D) and RSPO2 (E–H) is found more homogenously, with strong (A and E), but also moderate (B and F) to low (C and G) staining as well as immunonegative tumors. Most of the diffuse type gastric cancers (D and H) were classified low or negative for RSPO staining. Franziska Wilhelm et al. Mol Cancer Res 2017;15:776-785 ©2017 by American Association for Cancer Research